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Complex endoscopic examination in differential diagnosis of various macroscopical forms of lymphomas and cancer of stomach

Abstract

   Now there is a problem of timely diagnostics of malignant lymphoms as a result of expressed polymorphism of the visual picture frequently accepted for a cancer and other stomach diseases.
   Study objective. Increase of diagnostic efficacy of lymphomas and carcinoma of stomach using endosonographic method.
   Methods. The work was based on examination and treatment data of 29 patients with various macroscopical types of lymphoma and carcinoma of the stomach. To all patients intracavitary scanning and tumor biopsy was carried out after a video gastroscopy.
   Results. After visual examination in 8 (27.6%) observations we could not diagnose with full reliance a stomach lymphoma. Endosonography in 3 (10.3 %) cases signs of stomach lymphoma with typical thickening of submucosal layer was revealed. At 3 (10.3 %) patients were detected ultrasonic characteristics of infiltrative cancer, were visualised the hypoechogenic homogeneous mass which is starting with a mucosa, infiltrate submucosal and muscular layers that the differentiation of these layers has been completely disturbed. Only in 2 (6.9 %) cases among all patients we could not detail the diagnosis. Thus, endosonographic examination in 6 (20.7 %) patients of this group has specified the visual diagnosis, and in 21 (72.4 %) patient — has confirmed. Results was statistically significant (p < 0.05). Diagnostic value analysis of visual and endosonographic method in lymphoma revealing has shown significant superiority of the last. Its sensitivity 12 % over than visual endoscopic method, diagnostic accuracy — on 6.8 % above.

About the Authors

I. I. Kruglova
Samara Regional Clinical Oncologic Dispanser
Russian Federation

Samara



O. A. Malichova
Russian Academy of Medical Sciences
Russian Federation

N. N. Blokhin Russian Cancer Research Center

Moscow



Z. A. Suanova
Russian Academy for Postgraduate Medical Education
Russian Federation

Moscow



B. K. Poddubniy
Russian Academy for Postgraduate Medical Education
Russian Federation

Moscow



I. V. Poddubnaja
Russian Academy for Postgraduate Medical Education
Russian Federation

Moscow



References

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2. Труфанов Г. Е. Лучевая диагностика опухолей желудка / Г. Е. Труфанов [и др.] – СПб.: ЭЛБИ-СПб, 2007. – C. 7–17.

3. Чернеховская Н. Е. Эндоскопическая диагностика заболеваний пищевода, желудка и тонкой кишки / Н. Е. Чернеховская [и др.] – М.: МЕДпресс-информ, 2008. – 200 с.

4. Van Dam J., Sivak M. V. eds. Gastrointestinal Endosonography. Philadelphia: SAUNDERS, 1999. 296 p.


Review

For citations:


Kruglova I.I., Malichova O.A., Suanova Z.A., Poddubniy B.K., Poddubnaja I.V. Complex endoscopic examination in differential diagnosis of various macroscopical forms of lymphomas and cancer of stomach. Oncohematology. 2010;(2):20-24. (In Russ.)

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)