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Болезнь Кастлемана (обзор литературы)

https://doi.org/10.17650/1818-8346-2016-11-2-8-20

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Аннотация

Болезнь Кастлемана (ангиофолликулярная гиперплазия лимфатических узлов) – редкое доброкачественное лимфопролиферативное заболевание с длительным бессимптомным течением, ассоциированное с широким спектром аутоиммунных и онкологических заболеваний и риском развития неходжкинской лимфомы. Редкая встречаемость данного заболевания и разнообразие клинического течения не позволяют провести полноценные и последовательные исследования по изучению его этиологии и патогенеза, разработать стандартные методы терапии. В последние годы число пациентов с болезнью Кастлемана в Российской Федерации увеличилось, и это требует ее распознавания среди неопухолевых и опухолевых лимфаденопатий. Статья посвящена обзору данных о клинических и гистологических вариантах болезни Кастлемана, концепциях ее патогенеза, классификации и лечения.

Об авторах

А. Л. Меликян
ФГБУ «Гематологический научный центр» Минздрава России; Россия, 125167, Москва, Новый Зыковский проезд, 4а
Россия


Е. К. Егорова
ФГБУ «Гематологический научный центр» Минздрава России; Россия, 125167, Москва, Новый Зыковский проезд, 4а
Россия


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Для цитирования:


Меликян А.Л., Егорова Е.К. Болезнь Кастлемана (обзор литературы). Онкогематология. 2016;11(2):8-20. https://doi.org/10.17650/1818-8346-2016-11-2-8-20

For citation:


Melikyan A.L., Egorova E.K. Castleman disease (literature review). Oncohematology. 2016;11(2):8-20. (In Russ.) https://doi.org/10.17650/1818-8346-2016-11-2-8-20

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)