Diagnosis and monitoring of bone marrow involvement in Hodgkin's lymphoma using magnetic resonance imaging
https://doi.org/10.17650/1818-8346-2012-7-2-28-35
Abstract
In 42 patients with verified Hodgkin lymphoma and confirmed metastatic skeletal lesion possibility of using specific pulse sequences in imaging of bone marrow involvement have been established. MRI pattern of bone marrow lesion, signal localization, distribution and intensity were revealed. In 33 patients with newly diagnosed bone lesions the MR images of the affected and intact bone marrow during chemotherapy were assessed during 10 months. In 2 patients MR images were assessed after radiotherapy. Several MRI patterns changes of affected bone marrow after 2, 6 and 8 chemotherapy cycles were identified.
About the Authors
Z. N. ShavladzeRussian Federation
D. V. Neledov
Russian Federation
T. P. Berezovskaya
Russian Federation
References
1. Lister T.A., Crowther D., Sutcliffe S.B. et al. Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin’s disease: Cotswolds meeting. J Clin Oncol 1989;7(11):1630–6.
2. Reske S.N. Recent advances in bone marrow scanning. Eur J Nucl Med 1991;18(3):203–21.
3. Hoane B.R., Shields A.F., Porter B.A., Shulman H.M. Detection of lymphomatous bone marrow involvement with magnetic resonance imaging. Blood 1991;78(3): 728–38.
4. Курдыбайло Ф.В. Лимфогранулематоз. М.: Медицина, 1971. С. 37.
5. Murphy W.A., Destouet J.M., Gilula L.A. Percutaneous skeletal biopsy 1981: a procedure for radiologists – results, review, and recommendations. Radiology 1981;139(3):545–9.
6. Casamassima F., Ruggiero C., Caramella D. Hematopoietic bone marrow recovery after radiation therapy: MRI evaluation. Blood 1989;73(6):1677–81.
7. Hanna S.L., Fletcher B.D., Fairclough D.L. et al. Magnetic resonance imaging of disseminated bone marrow disease in patients treated for malignancy. Skeletal Radiol 1991;20(2):79–84.
8. Проскурина М.Ф., Стегачев С.Н., Юдин А.Л. Использование магнитно- резонансной томографии позвоночника при костномозговых опухолях и костных метастазах. Мед визуализация 2002;2:114–22.
9. Linden A., Zankovich R., Theissen P. et al. Malignant lymphoma: bone marrow imaging versus biopsy. Radiology 1989;173(2):335–9.
10. Thomas E.L., Saeed N., Hajnal J.V. et al. Magnetic resonance imaging of total body fat. J Appl Physiol 1998;85(5): 1778–85.
11. Walker R.E., Eustace S.J. Whole-body magnetic resonance imaging: techniques, clinical indications, and future applications. Semin Musculoskel Radiol 2001;5(1):5–20.
12. Dohner H., Gückel F., Knauf W. et al. Magnetic resonance imaging of bone marrow in lymphoproliferative disorders: correlation with bone marrow biopsy. Br J Haematol 1989;73(1):12–7.
13. Reske S.N. Recent advances in bone marrow scanning. Eur J Nucl Med 1991;18(3):203–21.
14. Vanel D., Bittoun J., Tardivon A. MRI of bone metastases. Eur Radiol 1998;8(8):1345–51.
15. Carrol K.W., Feller J.F., Tirman P.F. Useful internal standards for distinguishing infiltrative marrow pathology from ematopoietic marrow at MRI. J Magn Reson Imaging 1997;7(2):394–8.
16. Shields A.F., Porter B.A., Churchley S. et al. The detection of bone marrow involvement by lymphoma using magnetic resonance imaging. J Clin Oncol 1987;5(2):225–30.
17. Mundy G.R. Preclinical studies of metastasis: experimental models and novel techniques to detect micrometastases. Program and abstracts of 22nd San Antonio Brest Cancer Symposium; Desember 8–11. San Antonio, Texas, 1999.
18. Schmidt G.P., Reiser M.F., Baur-Melnyk A. Whole-body imaging of the musculoskeletal system: the value of MR imaging. Skeletal Radiol 2007;36(12):1109–19.
19. Rahmouni A., Divine M., Mathieu D. et al. MR appearance of multiple myeloma of the spine before and after treatment. Amer J Roentgenol 1993;160(5):1053–7.
20. Smith S.R., Roberts N., Percy D.F., Edwards R.H. Detection of bone marrow abnormalities in patients with Hodgkin’s disease by T1 mapping of MR images of lumbar vertebral bone marrow. Br J Cancer 1992;65(2):246–51.
21. Smith S.R., Williams C.E., Edwards R.H., Davies J.M. Quantitative magnetic resonance studies of lumbar vertebral marrow in patients with refractory or relapsed Hodgkin's disease. Ann Oncol 1991;2 Suppl 2: 39–42.
Review
For citations:
Shavladze Z.N., Neledov D.V., Berezovskaya T.P. Diagnosis and monitoring of bone marrow involvement in Hodgkin's lymphoma using magnetic resonance imaging. Oncohematology. 2012;7(2):28-35. (In Russ.) https://doi.org/10.17650/1818-8346-2012-7-2-28-35