Kikuchi–Fujimoto disease: literature review and report of four cases
V. G. Potapenko,
V. V. Baykov,
А. Yu. Markova,
N. B. Mikhailova,
A. S. Ter‑Grigoryan,
Yu. А. Krivolapov https://doi.org/10.17650/1818-8346-2022-17-4-48-59
Abstract
Kikuchi–Fujimoto disease, or necrotizing histiocytic lymphadenitis, is one of the rare causes of benign lymphadeno-pathy. The diagnosis is based on histological and immunohistochemical analysis of the lymph node biopsy. The article presents four clinical cases of Kikuchi–Fujimoto disease. According to the results of the primary analysis of lymph node tissue three patients were misdiagnosed with lymphoma. due to the unusual for lymphoid malignancy course the primary material was reviewed. The diagnosis of Kikuchi–Fujimoto disease was put. In three patients the disease has a re-current course. during the observation period, the course of the disease in all the presented patients is benign with normal quality of life.
About the Authors
V. G. Potapenko
City Clinical Hospital No. 31
Russian Federation
Russian Federation
Prospekt Dinamo, Saint Petersburg 197110
V. V. Baykov
Raisa Gorbacheva Memorial Research Institute for Pediatric Oncology, Hematology and Transplantation, I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
12 Rentgena St., Saint Petersburg 197022
А. Yu. Markova
City Hospital of the closed territorial unit Znamensk
Russian Federation
Russian Federation
1 Bolnichnaya St., Kapustin Yar 416510
N. B. Mikhailova
Raisa Gorbacheva Memorial Research Institute for Pediatric Oncology, Hematology and Transplantation, I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
12 Rentgena St., Saint Petersburg 197022
A. S. Ter‑Grigoryan
Hematological Center named after professor R.O. Yeolyan, Ministry of Health of the Republic of Armenia
Armenia
Armenia
7 Grachya Nersisyana St., Yerevan 0014
Yu. А. Krivolapov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
41 Kirochnaya St., Saint Petersburg 191015
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For citations:
Potapenko V.G., Baykov V.V., Markova А.Yu., Mikhailova N.B., Ter‑Grigoryan A.S., Krivolapov Yu.А. Kikuchi–Fujimoto disease: literature review and report of four cases. Oncohematology. 2022;17(4):48-59. (In Russ.) https://doi.org/10.17650/1818-8346-2022-17-4-48-59
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