Flow cytometry in the diagnosis of plasma cell tumors and assessment of minimal residual disease
https://doi.org/10.17650/1818-8346-2021-16-3-16-25
Abstract
The article considers the features and possibilities of flow cytometric diagnostics of plasma cell neoplasms, taking into account the classification of lymphoid and hematopoietic tissue tumors of the World Health Organization, revision of 2017 and the NCCN clinical recommendations, 2021. Standardized flow cytometric protocols (the Euro-Flow conception) and algorithms for both the diagnosis of plasma cell tumors and the detection of minimal residual disease in plasma cell myeloma are described.
About the Authors
L. Yu. Grivtsova
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
Lyudmila Yu. Grivtsova
10 Marshala Zhukova St., Obninsk 249031
T. Yu. Mushkarina
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
10 Marshala Zhukova St., Obninsk 249031
V. V. Lunin
Р.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 nd Botkinskiy Proezd, Moscow 125284
P. A. Zeynalova
Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
Russian Federation
Russian Federation
111 1st Uspenskoe Shosse, Lapino, Moscow region 143081
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Review
For citations:
Grivtsova L.Yu., Mushkarina T.Yu., Lunin V.V., Zeynalova P.A. Flow cytometry in the diagnosis of plasma cell tumors and assessment of minimal residual disease. Oncohematology. 2021;16(3):16-25. (In Russ.) https://doi.org/10.17650/1818-8346-2021-16-3-16-25
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