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Современные возможности терапии инфекций, вызванных карбапенеморезистентными энтеробактериями, у больных с опухолями системы крови

https://doi.org/10.17650/1818-8346-2020-15-2-92-107

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Аннотация

Инфекции являются частыми осложнениями у больных с опухолями системы крови, особенно в период нейтропении. В последнее время в этиологии инфекционных осложнений наблюдается увеличение количества полирезистентных грамотрицательных возбудителей, включая карбапенеморезистентные энтеробактерии, возможность терапии которых ограничена. В обзоре представлены варианты лечения инфекций, вызванных карбапенеморезистентными энтеробактериями, включающие как применение противомикробных препаратов резерва, таких как полимиксин, карбапенемы, тигециклин, так и нового антибиотика цефтазидима-авибактама, в состав которого входит новый ингибитор β-лактамаз с уникальными свойствами.

Об авторе

Г. А. Клясова
ФГБУ «Национальный медицинский исследовательский центр гематологии» Минздрава России
Россия

Галина Александровна Клясова

125167 Москва, Новый Зыковский проезд, 4



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Для цитирования:


Клясова Г.А. Современные возможности терапии инфекций, вызванных карбапенеморезистентными энтеробактериями, у больных с опухолями системы крови. Онкогематология. 2020;15(2):92-107. https://doi.org/10.17650/1818-8346-2020-15-2-92-107

For citation:


Klyasova G.A. Current treatment options for infections caused by carbapenem-resistant Enterobacteriaceae in patients with hematological malignancies. Oncohematology. 2020;15(2):92-107. (In Russ.) https://doi.org/10.17650/1818-8346-2020-15-2-92-107

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