The experience of free light chains of immunoglobulin elimination in patients with monoclonal gammopathies
E. G. Gromova,
P. A. Zeynalova,
N. V. Lubimova,
Yu. S. Timofeev,
N. E. Kushlinskiy,
A. A. Semenova,
V. V. Lunin,
Yu. I. Kluchagina https://doi.org/10.17650/1818-8346-2019-14-2-8-12
Abstract
The objective of study is to estimate the efficiency of extracorporeal free light chains of immunoglobulin elimination in patients with monoclonal gammopathies (n = 12) during hemodialysis using selective filters.
Materials and methods. A blood and dialysate free light chains concentrations change was criterion of efficiency.
Results and conclusion. The selective free light chains filtration give the possibility of an adequate anti-tumor therapy, could prevent the development of irreversible renal failure and hypoalbuminemia.
About the Authors
E. G. Gromova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
P. A. Zeynalova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
N. V. Lubimova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Yu. S. Timofeev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
N. E. Kushlinskiy
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
A. A. Semenova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
V. V. Lunin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Yu. I. Kluchagina
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478, Russia
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Review
For citations:
Gromova E.G., Zeynalova P.A., Lubimova N.V., Timofeev Yu.S., Kushlinskiy N.E., Semenova A.A., Lunin V.V., Kluchagina Yu.I. The experience of free light chains of immunoglobulin elimination in patients with monoclonal gammopathies. Oncohematology. 2019;14(2):8-12. (In Russ.) https://doi.org/10.17650/1818-8346-2019-14-2-8-12
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