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Т-клеточные лимфомы кожи: современные данные патогенеза, клиники и терапии

https://doi.org/10.17650/1818-8346-2018-13-3-25-38

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Аннотация

Т-клеточные лимфомы кожи (ТКЛК) представляют собой гетерогенную группу экстранодальных неходжкинских лимфом, которые характеризуются инфильтрацией кожи злокачественными моноклональными Т-лимфоцитами. Чаще болеют взрослые в возрасте от 55 до 60 лет, годовая заболеваемость составляет около 0,5 на 100 тыс. человек. Грибовидный микоз, синдром Сезари и СD30+ лимфопролиферативные заболевания являются основными подтипами ТКЛК. На сегодняшний день ТКЛК имеют сложную концепцию этиопатогенеза, диагностики, терапии и прогноза. В статье представлены обобщенные данные по этой проблеме.

Об авторах

О. М. Демина
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева» Минздрава России.
Россия
Ольга Михайловна Демина.
117997 Москва, ул. Саморы Машела, 1.


О. Е. Акилов
Клиника кожных лимфом, Университет Питтсбурга.
Соединённые Штаты Америки
15213 Питтсбург, Пятая авеню, 3601.


А. Г. Румянцев
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева» Минздрава России.
Россия
117997 Москва, ул. Саморы Машела, 1.


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Для цитирования:


Демина О.М., Акилов О.Е., Румянцев А.Г. Т-клеточные лимфомы кожи: современные данные патогенеза, клиники и терапии. Онкогематология. 2018;13(3):25-38. https://doi.org/10.17650/1818-8346-2018-13-3-25-38

For citation:


Demina O.M., Akilov O.E., Rumyantsev A.G. Cutaneous T-cell lymphomas: modern data of pathogenesis, clinics and therapy. Oncohematology. 2018;13(3):25-38. (In Russ.) https://doi.org/10.17650/1818-8346-2018-13-3-25-38

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