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Brentuximab vedotin in children and adolescents with Hodgkin’s lymphoma and anaplastic large cell lymphoma – literature review and own experience
- Authors: Myakova N.V.1,2, Evstratov D.A.1,2, Abramov D.S.1,2, Konovalov D.M.1,2, Pshonkin A.V.1,2, Litvinov D.V.1,2
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Affiliations:
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia
- 1 Samory Mashela St., Moscow, 117198, Russia
- Issue: Vol 11, No 1 (2016)
- Pages: 8-13
- Section: HEMATOLOGIC MALIGNANCIES: DIAGNOSIS, TREATMENT, SUPPORTIVE CARE
- Published: 31.03.2016
- URL: https://oncohematology.abvpress.ru/ongm/article/view/176
- DOI: https://doi.org/10.17650/1818-8346-2016-11-1-8-13
- ID: 176
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Abstract
Despite significant advances in the treatment of lymphomas in children remain a small proportion of patients with refractory or recurrent disease. An effective approach to the treatment of such patients – not only is the second line chemotherapy, but the use of the new targeted therapies. An example of this approach is the use of brentuximab vedotin (antibody-drug conjugate directed to the CD30) in relapsed Hodgkin’s lymphoma and anaplastic large cell lymphoma. Literature review and own experience of using this drug in children are describes in this article.
About the authors
N. V. Myakova
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, Russia
Author for correspondence.
Email: nmiakova@mail.ru
Russian Federation
D. A. Evstratov
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
D. S. Abramov
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
D. M. Konovalov
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
A. V. Pshonkin
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
D. V. Litvinov
Federal Research Institute of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
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