Personalized genotype-directed antitumor therapy for newly diagnosed diffuse large B-cell lymphoma: efficacy and toxicity of the R-CHOP-X protocol in a single-center, non-randomized, prospective clinical trial (first results)

M. A. Mingalimov; E. A. Baryakh; A. V. Misyurin; L. A. Kesaeva; A. S. Mkrtchyan; E. N. Misyurina; T. N. Tolstykh; M. S. Orlova; A. A. Akhmadeeva; T. S. Chudnova; D. D. Ivanova; O. L. Kochneva; E. N. Zotina; A. B. Makeshova; S. S. Andreev; K. V. Yatskov; I. V. Samsonova; M. A. Lysenko

Oncohematology
Onkogematologiâ

ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)

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Mingalimov M.A., Baryakh E.A., Misyurin A.V., Kesaeva L.A., Mkrtchyan A.S., Misyurina E.N., Tolstykh T.N., Orlova M.S., Akhmadeeva A.A., Chudnova T.S., Ivanova D.D., Kochneva O.L., Zotina E.N., Makeshova A.B., Andreev S.S., Yatskov K.V., Samsonova I.V., Lysenko M.A. Personalized genotype-directed antitumor therapy for newly diagnosed diffuse large B-cell lymphoma: efficacy and toxicity of the R-CHOP-X protocol in a single-center, non-randomized, prospective clinical trial (first results). Oncohematology. 2024;19(4):84-92. (In Russ.) https://doi.org/10.17650/1818-8346-2024-19-4-84-92

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)

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M. A. Mingalimov
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

E. A. Baryakh
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991;

Build. 1, 2/1 Barrikadnaya St., Moscow 125993

A. V. Misyurin
Vavilov Institute of General Genetics, Russian Academy of Sciences
Russian Federation

3 Gubkina St., Moscow 119991

L. A. Kesaeva
GeneTechnology
Russian Federation

104 Profsoyuznaya St., Moscow 117437

A. S. Mkrtchyan
GeneTechnology
Russian Federation

104 Profsoyuznaya St., Moscow 117437

E. N. Misyurina
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

T. N. Tolstykh
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

M. S. Orlova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

Build. 2, 8 Trubetskaya St., Moscow 119991

A. A. Akhmadeeva
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

Build. 2, 8 Trubetskaya St., Moscow 119991

T. S. Chudnova
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

D. D. Ivanova
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

O. L. Kochneva
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

E. N. Zotina
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

A. B. Makeshova
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

S. S. Andreev
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

K. V. Yatskov
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

I. V. Samsonova
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

M. A. Lysenko
City Clinical Hospital No. 52, Moscow Healthcare Department; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

3 Pekhotnaya St., Moscow 123182;

Build. 2, 8 Trubetskaya St., Moscow 119991

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