Клиническое значение инфекций, вызванных вирусами герпеса человека 6А и 6B, у реципиентов аллогенных гемопоэтических стволовых клеток в посттрансплантационном периоде

Трансплантация аллогенных гемопоэтических стволовых клеток – эффективный метод терапии гемобластозов и неопухолевых заболеваний системы крови. Инфекции, вызванные вирусами герпеса человека 6A и 6B, являются одной из лидирующих причин осложнений и смертности пациентов гематологического профиля после трансплантации аллогенных гемопоэтических стволовых клеток, особенно в первые 100 дней после трансплантации. В данном обзоре рассматриваются клинические особенности инфекций, вызванных вирусами герпеса человека 6A и 6B, их влияние на развитие посттрансплантационных осложнений, в том числе реакции «трансплантат против хозяина» и несостоятельности трансплантата, а также методы профилактики и лечения.

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