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Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome

https://doi.org/10.17650/1818-8346-2024-19-3-149-152

Abstract

Evaluation of bone marrow cytogenetic abnormalities in myelodysplastic syndrome is of great importance for confirming the clonal disease nature, determining the prognosis and choosing treatment tactics. Cytogenetic abnormalities are detected in 40–70 % of patients with myelodysplastic syndrome, and the variety of these abnormalities reflects the disease characteristics.

This article describes the clinical follow-up of a patient with a myelodysplastic neoplasia with blast excess 1 and trisomy of chromosome 14.

About the Authors

M. N. Pautova
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation

Marina N. Pautova 

41 Kirochnaya St., Saint Petersburg 191015



L. E. Koloskova
Medical Laboratory SPb
Russian Federation

71A Obukhovskoy Oborony Prospekt, Saint Petersburg 192029



O. I. Filippova
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation

41 Kirochnaya St., Saint Petersburg 191015



A. V. Koloskov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation

41 Kirochnaya St., Saint Petersburg 191015



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Review

For citations:


Pautova M.N., Koloskova L.E., Filippova O.I., Koloskov A.V. Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome. Oncohematology. 2024;19(3):149-152. (In Russ.) https://doi.org/10.17650/1818-8346-2024-19-3-149-152

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)