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Clinical case of giant extramedullar plasmacytoma in a patient with multiple myeloma

https://doi.org/10.17650/1818-8346-2023-18-4-58-63

Abstract

One possible manifestation of multiple myeloma may be extramedullary plasmacytoma, manifested by infiltration of plasma cells outside the bone marrow. In the debut of the disease, bone plasmacytomas are most often diagnosed, in contrast to extramedullary ones, which are rare. According to the literature, the presence of extramedullary plasmacytoma is an unfavorable factor characterized by an aggressive disease course, the absence of an antitumor response to standard therapy, and low overall survival rates. Therefore, the pathogenesis, clinic, diagnosis and treatment of this variant of the disease require additional study. This article presents a clinical case of an aggressive course of extensive extramedullary plasmacytoma in a patient with multiple myeloma with an assessment of various combination therapy regimens efficacy.

About the Authors

G. Sh. Safuanova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation

Guzyal Sh. Safuanova 

3 Lenina St., Ufa 450008



Yu. R. Mansurova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation

3 Lenina St., Ufa 450008



A. A. Latypova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

132 Dostoevskogo St., Ufa 450005



А. U. Bagautdinova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

132 Dostoevskogo St., Ufa 450005



T. Yu. Rozhenkova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

132 Dostoevskogo St., Ufa 450005



Ch. Kh. Valiakhmetova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

132 Dostoevskogo St., Ufa 450005



References

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Review

For citations:


Safuanova G.Sh., Mansurova Yu.R., Latypova A.A., Bagautdinova А.U., Rozhenkova T.Yu., Valiakhmetova Ch.Kh. Clinical case of giant extramedullar plasmacytoma in a patient with multiple myeloma. Oncohematology. 2023;18(4):58-63. (In Russ.) https://doi.org/10.17650/1818-8346-2023-18-4-58-63

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)