Combination of multiple myeloma and chronic idiopathic myelofibrosis: a case report
https://doi.org/10.17650/1818-8346-2009-0-3-61-68
Abstract
Case report of a patient with simultaneously developed lymphoid and myeloid hemoblastosis is presented. Diagnosis of multiple myeloma and chronic idiopathic myelofibrosis are confirmed by complete blood count, myelogramm, trephinebiopsy, immunohistochemical, cytogenetic, biochemical and radiological examination. Complete remission of multiple myeloma was achieved after 7 courses «VAD» and 11-weeks treatment with recombinant erythropoietin beta with subsequent maintenance therapy courses of bortezomib and reaferon. However, chronic idiopathic myelofibrosis was progressed to acute myeloid leukemia. Disease stabilization was achieved with 3 therapy courses «5+2».
About the Authors
N. A. Romanenko
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
S. S. Bessmeltsev
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
V. I. Rugal
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
N. A. Potichonova
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
M. N. Zenina
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
K. M. Abdulkadirov
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
St-Petersburg
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Review
For citations:
Romanenko N.A., Bessmeltsev S.S., Rugal V.I., Potichonova N.A., Zenina M.N., Abdulkadirov K.M. Combination of multiple myeloma and chronic idiopathic myelofibrosis: a case report. Oncohematology. 2009;(3):61-68. (In Russ.) https://doi.org/10.17650/1818-8346-2009-0-3-61-68
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