The prognostic value of posttransplant chimerism

A. A. Sipol; Сипол А. А.; E. V. Semenova; Семенова Е. В.; I. M. Barkchato; Бархатов И. М.; M. S. Vedjukova; Ведюкова М. С.; I. S. Solomonova; Соломонова И. С.; M. V. Prjanishnikova; Прянишникова М. В.; A. B. Chukchlovin; Чухловин А. Б.; L. S. Zoubarovskaja; Зубаровская Л. С.; B. V. Afanasyev; АфанасьевБ.В. Б. В.

doi:10.17650/1818-8346-2008-0-4-31-35

The prognostic value of posttransplant chimerism

Authors: Sipol A.A.¹^,2, Semenova E.V.¹^,2, Barkchato I.M.¹^,2, Vedjukova M.S.¹^,2, Solomonova I.S.¹^,2, Prjanishnikova M.V.¹^,2, Chukchlovin A.B.¹^,2, Zoubarovskaja L.S.¹^,2, Afanasyev B.V.¹^,2
Affiliations:
1. Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantology
2. Saint-Petersburg Pavlov State Medical University
Issue: No 4 (2008)
Pages: 31-35
Section: HEMATOPOIETIC STEM CELL TRANSPLANTATION
Published: 25.11.2008
URL: https://oncohematology.abvpress.ru/ongm/article/view/750
DOI: https://doi.org/10.17650/1818-8346-2008-0-4-31-35
ID: 750

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Abstract

Overall survival and relapse rates in 62 patients after allogeneic hemopoietic stem cells transplantation according to posttransplantation chimerism values are presented. Significant differences in 5-year overall survival rate have been found in patients with complete donor and mixed chimerism on days 30 and 100 after transplantation with myeloablative conditioning regimens. The influence of chimerism in different time point after transplantation for relapse rate is shown.