Differential diagnosis of non-Hodgkin's B-cell lymphomas
https://doi.org/10.17650/1818-8346-2007-0-2-4-9
Abstract
This article reviews the problems of morphological and immunohistochemical diagnosis of non-Hodgkin's B-cell lymphomas. We compared immunophenotype of B-cell lymphoid neoplasms and their «normal cell» analogs taking into account 4 stages during B-cell differentiation: bone marrow B-cell precursors, mature naive B cells, B cells with follicular differentiation, and postfollicular B cells. We proposed an algorithm of immunohistochemical differential diagnosis.
About the Authors
A. M. Kovrigina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
Moscow
N. A. Probatova
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Kovrigina A.M., Probatova N.A. Differential diagnosis of non-Hodgkin's B-cell lymphomas. Oncohematology. 2007;(2):4-9. (In Russ.) https://doi.org/10.17650/1818-8346-2007-0-2-4-9
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