Hypercalcemia associated with hematologic malignancies
https://doi.org/10.17650/1818-8346-2007-0-2-59-62
Abstract
Гиперкальциемия, развившаяся на фоне онкологического заболевания, значительно ухудшает непосредственный прогноз: около половины пациентов с клинически значимой гиперкальциемией умирают в течение 1 мес [1], при этом степень выраженности гиперкальциемии и ее симптомов вовсе не свидетельствует об инкурабельности самого онкологического заболевания.
About the Authors
I. A. KurmukovRussian Federation
Sh. R. Kashia
Russian Federation
References
1. Ralston S.H., Gallagher S.J., Patel U. et al. Cancer-associated hypercalcemia: morbidity and mortality: clinical experience in 126 treated patients. Ann Intern Med 1990;112:499—504.
2. John R., Oleesky D., Issa B. et al. Pseudohypercalcaemia in two patients with IgM paraproteinaemia. Ann Clin Biochem 1997; 34:694—6.
3. Stewart A.F. Hypercalcemia Associated with Cancer. N Engl J Med 2005;352:373—9.
4. Bilezikian J.P., Silverberg S.J. Asymptomatic primary hyperparathyroidism. N Engl J Med 2004;350: 1746—51.
5. LeBoff M.S., Mikulec K.H. Hypercalcemia: clinical manifestations, pathogenesis, diagnosis, and management. In: M.J. Favus (eds.). Primer on the metabolic bone diseases and disorders of mineral metabolism. 5th ed. Washington D.C., American Society for Bone and Mineral Research; 2003. p. 225—30.
6. Fleisch H. Bisphosphonates: mechanisms of action. Endocr Rev 1998;19:80—100.
7. Markowitz G.S., Fine P.L., Stack J.I. et al. Toxic acute tubular necrosis following treatment with zoledronate (Zometa). Kidney Int 2003;64:281—9.
8. Pecherstorfer M., Steinhauer E.U., Rizzoli R. et al. Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate. Support Care Cancer 2003;11:539—47.
9. von Moos R. Bisphosphonate Treatment Recommendations for Oncologists. The Oncologist 2005;10 (Suppl 1):19—24.
10. Binstock M.L., Mundy G.R. Effect of calcitonin and glucocorticoids in combination on the hypercalcemia of malignancy. Ann Intern Med 1980;93:269—72.
11. Koo W.S., Jeon D.S., Ahn S.J. et al. Calcium-free hemodialysis for the management of hypercalcemia. Nephron 1996;72:424—8.
Review
For citations:
Kurmukov I.A., Kashia Sh.R. Hypercalcemia associated with hematologic malignancies. Oncohematology. 2007;(2):59-62. (In Russ.) https://doi.org/10.17650/1818-8346-2007-0-2-59-62