Preview

Oncohematology

Advanced search

A clinical case of extramedullary skin lesion in a patient with acute myelomonocytic leukemia

https://doi.org/10.17650/1818-8346-2022-17-2-43-50

Abstract

Acute myelomonocytic leukemia is a rare form of leukemia, in which the bone marrow is damaged by morphologically immature, tumor cells, which subsequently displace the normal cellular composition and involve other body systems in the pathological process. Among all acute myeloid leukemias, 5–30 % is the myelomonocytic form. The peculiarity of this form of leukemia is the extramedullary manifestations – leukemides, the appearance of which most often indicates an unfavorable prognosis. The article discusses a clinical case of acute myelomonocytic leukemia with the development of extramedullary skin lesions (leukemides) in a patient.

About the Authors

G. S. Safuanova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation

450008, Ufa, Lenina St., 3



I. V. Ivanova
Bashkir State Medical University, Ministry of Health of Russia
Russian Federation

450008, Ufa, Lenina St., 3



A. A. Latypova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

450005, Ufa, Dostoevskogo St., 132



E. G. Tsareva
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

450005, Ufa, Dostoevskogo St., 132



V. I. Akhunova
G.G. Kuvatov Republican Clinical Hospital
Russian Federation

450005, Ufa, Dostoevskogo St., 132



D. R. Safuanova
National Research Center for Hematology, Ministry of Health of Russia
Russian Federation

125167, Moscow, Novyy Zykovskiy Proezd, 4



References

1. Hematology: national guidelines. Ed.: O.A. Rukavitsin. Moscow: GEOTARMedia, 2019. Pp. 180–219. (In Russ.).

2. Diagnostic algorithms and treatment protocols for blood system disoders. Ed.: V.G. Savchenko. Vol. 1. Moscow: Praktika, 2018. Pp. 501–526. (In Russ.).

3. Grebenyuk L.A., Obukhova T.N., Parovichnikova E.N. et al. Anomalies of chromosomes 5, 7, 11, and 17 in complex karyotype in myelodysplastic syndromes and acute myeloid leukemias. Meditsinskaya genetika = Medical Genetics 2018;17(6):39–47. (In Russ.). DOI:10.25557/2073-7998.2018.06.39-47.

4. Savchenko V.G., Parovichnikova E.N., Afanas’ev B.V. et al. Clinical recommendations for diagnostics and treatment of adult acute myeloid leukemia. 2018. Pp. 5–63. (In Russ.).

5. Mustafakulova N.I., Rakhmonova O.D., Dzhamilov D.D. The prognostic significance of skin manifestations and early hematological parameters in various forms of leukemia. Vestnik Avitsenny = Avicenna Bulletin 2012;2(51):121–5. (In Russ.). DOI:10.25005/2074-0581-2012-14-2121-125.


Review

For citations:


Safuanova G.S., Ivanova I.V., Latypova A.A., Tsareva E.G., Akhunova V.I., Safuanova D.R. A clinical case of extramedullary skin lesion in a patient with acute myelomonocytic leukemia. Oncohematology. 2022;17(2):43-50. (In Russ.) https://doi.org/10.17650/1818-8346-2022-17-2-43-50

Views: 10961


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)