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A clinical case of extramedullary skin lesion in a patient with acute myelomonocytic leukemia
- Authors: Safuanova G.S.1, Ivanova I.V.1, Latypova A.A.2, Tsareva E.G.2, Akhunova V.I.2, Safuanova D.R.3
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Affiliations:
- Bashkir State Medical University, Ministry of Health of Russia
- G.G. Kuvatov Republican Clinical Hospital
- National Research Center for Hematology, Ministry of Health of Russia
- Issue: Vol 17, No 2 (2022)
- Pages: 43-50
- Section: RARE AND COMPLEX CLINICAL SITUATIONS: DIAGNOSTIC DIFFICULTIE AND TREATMENT CHOICE
- Published: 12.04.2022
- URL: https://oncohematology.abvpress.ru/ongm/article/view/537
- DOI: https://doi.org/10.17650/1818-8346-2022-17-2-43-50
- ID: 537
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Abstract
Acute myelomonocytic leukemia is a rare form of leukemia, in which the bone marrow is damaged by morphologically immature, tumor cells, which subsequently displace the normal cellular composition and involve other body systems in the pathological process. Among all acute myeloid leukemias, 5–30 % is the myelomonocytic form. The peculiarity of this form of leukemia is the extramedullary manifestations – leukemides, the appearance of which most often indicates an unfavorable prognosis. The article discusses a clinical case of acute myelomonocytic leukemia with the development of extramedullary skin lesions (leukemides) in a patient.
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About the authors
G. S. Safuanova
Bashkir State Medical University, Ministry of Health of Russia
Author for correspondence.
Email: safuanova@bk.ru
ORCID iD: 0000-0003-2627-0626
450008, Ufa, Lenina St., 3
Russian FederationI. V. Ivanova
Bashkir State Medical University, Ministry of Health of Russia
ORCID iD: 0000-0002-1492-5667
450008, Ufa, Lenina St., 3
Russian FederationA. A. Latypova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0000-0002-9508-3878
450005, Ufa, Dostoevskogo St., 132
Russian FederationE. G. Tsareva
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0000-0002-4815-0484
450005, Ufa, Dostoevskogo St., 132
Russian FederationV. I. Akhunova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0000-0002-3673-2356
450005, Ufa, Dostoevskogo St., 132
Russian FederationD. R. Safuanova
National Research Center for Hematology, Ministry of Health of Russia
ORCID iD: 0000-0001-7944-8585
125167, Moscow, Novyy Zykovskiy Proezd, 4
Russian FederationReferences
- Hematology: national guidelines. Ed.: O.A. Rukavitsin. Moscow: GEOTARMedia, 2019. Pp. 180–219. (In Russ.).
- Diagnostic algorithms and treatment protocols for blood system disoders. Ed.: V.G. Savchenko. Vol. 1. Moscow: Praktika, 2018. Pp. 501–526. (In Russ.).
- Grebenyuk L.A., Obukhova T.N., Parovichnikova E.N. et al. Anomalies of chromosomes 5, 7, 11, and 17 in complex karyotype in myelodysplastic syndromes and acute myeloid leukemias. Meditsinskaya genetika = Medical Genetics 2018;17(6):39–47. (In Russ.). doi: 10.25557/2073-7998.2018.06.39-47.
- Savchenko V.G., Parovichnikova E.N., Afanas’ev B.V. et al. Clinical recommendations for diagnostics and treatment of adult acute myeloid leukemia. 2018. Pp. 5–63. (In Russ.).
- Mustafakulova N.I., Rakhmonova O.D., Dzhamilov D.D. The prognostic significance of skin manifestations and early hematological parameters in various forms of leukemia. Vestnik Avitsenny = Avicenna Bulletin 2012;2(51):121–5. (In Russ.). doi: 10.25005/2074-0581-2012-14-2121-125.
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