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Successful treatment of pulmonary mucormycosis in a child with aplastic anemia

https://doi.org/10.17650/1818-8346-2013-8-1-52-58

Abstract

Mucormycosis (zygomycosis) is a frequently fatal fungal infection in immunocompromized patients. We describe a case of a successfull treatment of pulmonary mucormycosis in 11-year-child with a very severe aplastic anemia. The diagnosis of invasive mycosis has been proved according to EORTC 2008 criteria. Computed tomography showed bilobar right-sided pulmonary infiltration. Lichtheimia corymbifera cultured from BAL. The child achieved complete clinical, laboratory and instrumental response on long-term amphotericin B lipid-formulated therapy combined with posaconazole.

About the Authors

Ye. A. Nikitina
Children Municipal Hospital № 1
Russian Federation


N. N. Klimko
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation


A. S. Kolbin
Saint Petersburg State University
Russian Federation


E. G. Boychenko
Children Municipal Hospital № 1
Russian Federation


I. A. Garbuzova
Children Municipal Hospital № 1
Russian Federation


M. V. Golubeva
Children Municipal Hospital № 1
Russian Federation


T. S. Bogomolova
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation


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Review

For citations:


Nikitina Ye.A., Klimko N.N., Kolbin A.S., Boychenko E.G., Garbuzova I.A., Golubeva M.V., Bogomolova T.S. Successful treatment of pulmonary mucormycosis in a child with aplastic anemia. Oncohematology. 2013;8(1):52-58. (In Russ.) https://doi.org/10.17650/1818-8346-2013-8-1-52-58

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)