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ВЕНЕТОКЛАКС В ЛЕЧЕНИИ ХРОНИЧЕСКОГО ЛИМФОЛЕЙКОЗА (обзор литературы)

https://doi.org/10.17650/1818-8346-2018-13-2-32-38

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Аннотация

В последние годы достигнуты большие успехи в понимании биологии и механизмов развития хронического лимфолейкоза. Ведущее звено в патогенезе заболевания – резистентность опухолевых клеток к апоптозу. Один из основных регуляторов процессов программированной клеточной гибели – белки семейства Bcl-2. Признание важной роли белка Bcl-2 в развитии опухоли сделало его привлекательной мишенью для терапевтического воздействия. Данный обзор посвящен значению препарата венетоклакс (селективный ингибитор антиапоптотического белка Bcl-2) в лечении хронического лимфолейкоза.

Об авторе

Т. Е. Бялик
ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России
Россия

Татьяна Евгеньевна Бялик 

115478 Москва, Каширское шоссе, 23



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Для цитирования:


Бялик Т.Е. ВЕНЕТОКЛАКС В ЛЕЧЕНИИ ХРОНИЧЕСКОГО ЛИМФОЛЕЙКОЗА (обзор литературы). Онкогематология. 2018;13(2):32-38. https://doi.org/10.17650/1818-8346-2018-13-2-32-38

For citation:


Byalik T.E. VENETOCLAX IN TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (literature review). Oncohematology. 2018;13(2):32-38. (In Russ.) https://doi.org/10.17650/1818-8346-2018-13-2-32-38

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ISSN 1818-8346 (Print)
ISSN 2413-4023 (Online)