Basic mechanisms of iron metabolism regulation and their clinical significance
https://doi.org/10.17650/1818-8346-2014-9-3-67-71
Abstract
This article is а composition of literature and experimental data of iron metabolism. There were studied the level of DMT-1, ferroportin, hepcidin at different stages of anemia and hemochromatosis. It is clear that the level of DMT-1 regulates by the hepcidin. Increaseing of the hepcidin concentration and decreasing DMT-1 level in patients with hemochromatosis explained good results of treatment.
About the Authors
L. M. Meshсheryakova
Hematologic Scientific Center, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
A. A. Levina
Outpatient center “City polyclinic № 62”, Moscow Department of Health Care
Russian Federation
Russian Federation
M. M. Tsybulskaya
Outpatient center “City polyclinic № 62”, Moscow Department of Health Care
Russian Federation
Russian Federation
T. V. Sokolova
Outpatient center “City polyclinic № 62”, Moscow Department of Health Care
Russian Federation
Russian Federation
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Review
For citations:
Meshсheryakova L.M., Levina A.A., Tsybulskaya M.M., Sokolova T.V. Basic mechanisms of iron metabolism regulation and their clinical significance. Oncohematology. 2014;9(3):67-71. (In Russ.) https://doi.org/10.17650/1818-8346-2014-9-3-67-71
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