Kidney damage in chronic lymphocytic leukemia
https://doi.org/10.17650/1818-8346-2025-20-3-39-46
Abstract
Chronic lymphocytic leukemia is the most common type of leukemia in adults. Kidney damage can be diagnosed at the onset of the disease or during its progression, relapse. In most studies, kidney damage in this disease was verified by the results of biopsy. Studies of recent decades have identified a wide range of kidney lesions in chronic lymphocytic leukemia, including lymphoid infiltration of parenchyma, glomerular and tubular damage caused by a monoclonal protein (M-protein) produced by B cells, thrombotic microangiopathy, worsening of comorbid pathology, additional infection, paraneoplastic reactions, tumor lysis syndrome, and drug-induced toxic kidney injury with damage of glomeruli, tubules, or renal vessels.
In this article, we consider various forms of kidney disease associated with chronic lymphocytic leukemia.
About the Authors
V. V. Cherepanova
National Research Lobachevsky State University of Nizhny Novgorod
Russian Federation
Russian Federation
Valentina Vasil’evna Cherepanova
23 Gagarina Prospekt, Nizhniy Novgorod 603022
A. D. Saydov
City Clinical Hospital No. 38, Nizhny Novgorod Ministry of Health
Russian Federation
Russian Federation
22 Chernyshevskogo St., Nizhniy Novgorod 603000
Z. D. Mikhaylova
City Clinical Hospital No. 38, Nizhny Novgorod Ministry of Health
Russian Federation
Russian Federation
22 Chernyshevskogo St., Nizhniy Novgorod 603000
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Review
For citations:
Cherepanova V.V., Saydov A.D., Mikhaylova Z.D. Kidney damage in chronic lymphocytic leukemia. Oncohematology. 2025;20(3):39-46. (In Russ.) https://doi.org/10.17650/1818-8346-2025-20-3-39-46
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