5q– as the only cytogenetic abnormality in myelodysplastic syndrome with blast excess

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Abstract

Cytogenetic studies are required for the diagnosis of myelodysplastic neoplasms (MDS) because the World Health Organization 2022 classification divides MDS into a group with defined genetic abnormalities and MDS that are defined morphologically. Additionally, this paper modifies the terminology to clarify the distinction between MDS with low (<5 % in bone marrow) and increased blast cell counts (5–9 % for MDS with blast excess 1 and 10–19 % for MDS with blast excess 2).

This article describes the clinical observation of a patient with blast excess MDS and isolated 5q deletion.

About the authors

M. N. Pautova

City Hospital No. 26

Author for correspondence.
Email: paytova.marinaa@gmail.com
ORCID iD: 0009-0004-7215-791X

Marina Nikolaevna Pautova 

2 Kostyushko St., Saint Petersburg 196247

Russian Federation

L. E. Koloskova

Medical Laboratory SPb

ORCID iD: 0000-0002-5221-8832

4H, lit. A, 71 Obukhovskoy Oborony Prospekt, Saint Petersburg 192029

Russian Federation

A. V. Koloskov

City Hospital No. 26

ORCID iD: 0000-0002-5249-4255

2 Kostyushko St., Saint Petersburg 196247

Russian Federation

V. N. Marchenko

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

ORCID iD: 0000-0002-2440-7222

 6–8 L’va Tolstogo St., Saint Petersburg 197022

Russian Federation

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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