OncohematologyOncohematologyОнкогематология1818-83462413-4023Publishing House ABV Press810.17650/1818-8346-2014-9-1-25-34HEMATOPOIETIC STEM CELL TRANSPLANTATIONТРАНСПЛАНТАЦИЯ ГЕМОПОЭТИЧЕСКИХ СТВОЛОВЫХ КЛЕТОК У ПАЦИЕНТОВ С ГЕМОБЛАСТОЗАМИResting energy expenditure and body composition in children with cancer: indirect calorimetry and bioimpedance analysisИсследование энерготрат покоя и состава тела у детей и подростков с онкологическими заболеваниями: непрямая калориметрия и биоимпедансный анализKonovalovaM. V.КоноваловаМ. В.
Russian Federation
RudnevS. G.РудневС. Г.
Russian Federation
TseytlinG. Ya.ЦейтлинГ. Я.
Russian Federation
grigoryts@yandex.ruVashuraA. Yu.ВашураА. Ю.
Russian Federation
StarunovaO. A.СтаруноваО. А.
Russian Federation
NikolaevD. V.НиколаевД. В.
Russian Federation
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of RussiaФГБУ ФНКЦ ДГОИ им. Дмитрия Рогачева Минздрава РоссииInstitute of Numerical Mathematics, Russian Academy of SciencesИнститут вычислительной математики РАНScientific Technical Centre “Medas”ЗАО Научно-технический центр «Медасс»Scientific Technical Centre “Medas”ЗАО Научно-технический центр «Медасс»,210720149125342107201421072014https://oncohematology.abvpress.ru/ongm/article/view/8

Resting energy expenditure (REE) by indirect calorimetry and body composition by bioimpedance analysis are studied in three groups of children aged 5–18 years. Group 1 (n = 181) – patients in remission of cancer, group 2 (n = 55) – children with oncology diseases receiving chemotherapy or who are in the early period after hematopoietic stem cell transplantation, group 3 (n = 63) – children with non-malignant diseases of the gastrointestinal tract. To eliminate the influence of age and gender on the intergroup comparisons, body composition parameters were expressed as standardized values (z-scores) relative to a reference group of healthy Russian children (n = 138,191). Group 1 was characterized by excess fat content with intact lean body mass, and groups 2 and 3 by protein depletion, more pronounced in Group 2 with a higher percentage of body fat. All used conventional formulas (WHO, Harris–Benedict and others) in groups 1 and 3 underestimated REE as compared with indirect calorimetry. A new formula for REE, giving an unbiased estimate in the group 1 was proposed: REE (kcal/day) = 28.7 × BCM (kg) +10.5 × Height (cm) – 38.6 × Age (years) – 134, where BCM – body cell mass according to bioimpedance analysis (R2 = 0.67, the standard deviation of 196 kcal/day).

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