OncohematologyOncohematologyОнкогематология1818-83462413-4023Publishing House ABV Press74410.17650/1818-8346-2008-0-4-5-10HEMATOLOGIC MALIGNANCIES: TREATMENT, SUPPORTIVE CAREГЕМОБЛАСТОЗЫ: ЛЕЧЕНИЕ, СОПРОВОДИТЕЛЬНАЯ ТЕРАПИЯPrimary lymphatic tumors of bones: two case reports and a review of literatureПервичные лимфатические опухоли костей: описание двух случаев и обзор литературыEgorovaE. K.ЕгороваЕ. К.
Russian Federation

Moscow

Москва

GabeevaN. G.ГабееваН. Г.
Russian Federation

Moscow

Москва

MamonovV. Ye.МамоновВ. Е.
Russian Federation

Moscow

Москва

MaryinD. S.МарьинД. С.
Russian Federation

Moscow

Москва

KaplanskayaI. B.КапланскаяИ. Б.
Russian Federation

Moscow

Москва

ZvonkovE. E.ЗвонковЕ. Е.
Russian Federation

Moscow

Москва

MagomedovaA. U.МагомедоваА. У.
Russian Federation

Moscow

Москва

KravchenkoS. K.КравченкоС. К.
Russian Federation

Moscow

Москва

KremenestskayaA. M.КременецкаяА. М.
Russian Federation

Moscow

Москва

Hematological Research Center, Russian Academy of Medical SciencesГематологический научный центр РАМН25112008451025112022251120222008https://oncohematology.abvpress.ru/ongm/article/view/744

Primary bone lymphoma (PBL) is a rare disease. In this article two cases of primary diffuse large B-cell lymphoma of bones are described, one case of solitary lesion and the other of multiple lesions. Both patients were treated with courses CHOEP in combination with radiotherapy and achieved a complete remission (CR). The patient with solitary lesion is still in CR with the follow-up of 33 months. The patient with multiple lesions where partial remission has been received died in 3 months after the end of therapy from disease progression. The authors discuss differential diagnosis and present a review of literature concerning PBL.

Первичная лимфома костей - редкое заболевание. В данной статье мы описываем 2 случая первичной диффузной В-крупноклеточной лимфомы костей, один с солитарным и другой — с множественным поражением. Оба пациента пролечены по схеме СНОЕР-21 с применением лучевой терапии, достигнута полная ремиссия. Больной с солитарным поражением находится в полной ремиссии в течение 33 мес. Пациент с множественным поражением, у которого была получена частичная ремиссия, умер через 3 мес после окончания лечения от прогрессии основного заболевания. Обсуждается дифференциальная диагностика и приведен обзор литературы, касающиеся первичной лимфомы костей.

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