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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Oncohematology</journal-id><journal-title-group><journal-title xml:lang="en">Oncohematology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкогематология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8346</issn><issn publication-format="electronic">2413-4023</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">625</article-id><article-id pub-id-type="doi">10.17650/1818-8346-2007-0-1-52-56</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>NOVEL DATA ON WELL-KNOWN DRUGS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>НОВОЕ ОБ ИЗВЕСТНЫХ ПРЕПАРАТАХ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The abilities of adequate choice of different asparaginase products</article-title><trans-title-group xml:lang="ru"><trans-title>Возможности адекватного выбора различных препаратов аспарагиназы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Popa</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Попа</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">НИИ детской онкологии и гематологии РОНЦ им. Н.Н. Блохина, РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2007-02-22" publication-format="electronic"><day>22</day><month>02</month><year>2007</year></pub-date><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>52</fpage><lpage>56</lpage><history><date date-type="received" iso-8601-date="2022-11-22"><day>22</day><month>11</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-11-22"><day>22</day><month>11</month><year>2022</year></date></history><permissions><copyright-year>2007</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncohematology.abvpress.ru/ongm/article/view/625">https://oncohematology.abvpress.ru/ongm/article/view/625</self-uri><abstract xml:lang="en"><p>.</p></abstract><trans-abstract xml:lang="ru"><p>.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1.	Kidd J.G. Regression of transplanted lymphomas induced in vivo by means of normal guinea-pig serum: I. Course of transplanted cancer of various kinds in mice and rats given guinea-pig serum , horse serum or rabbit serum. J Exp Med 1953;98:568—82.</mixed-citation><mixed-citation xml:lang="ru">Kidd J.G. Regression of transplanted lymphomas induced in vivo by means of normal guinea-pig serum: I. Course of transplanted cancer of various kinds in mice and rats given guinea-pig serum , horse serum or rabbit serum. J Exp Med 1953;98:568—82.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2.	Sobin L.H., Kidd J.G. The incorporation of l-asparagin-14C by lymphoma 6C3HED cells: its inhibition by guinea-pig serum. Cancer Res 1966;26(2):208—11.</mixed-citation><mixed-citation xml:lang="ru">Sobin L.H., Kidd J.G. The incorporation of l-asparagin-14C by lymphoma 6C3HED cells: its inhibition by guinea-pig serum. Cancer Res 1966;26(2):208—11.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3.	Sobin L.H., Kidd J.G. Alterations in protein and nucleic acid metabolism of lymphoma 6C3HED-og cellas in mice given guinea-pig serum. J Exp Med 1966;123(1):55—74.</mixed-citation><mixed-citation xml:lang="ru">Sobin L.H., Kidd J.G. Alterations in protein and nucleic acid metabolism of lymphoma 6C3HED-og cellas in mice given guinea-pig serum. J Exp Med 1966;123(1):55—74.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4.	Broome J.D. Antilymphoma activity of L-asparaginase in vivo: clearance rate of enzyme preparations from guinea-pig serum and yeast in relation of their effects on tumor growth. J Natl Acad Sci U S A 1965;35:967—74.</mixed-citation><mixed-citation xml:lang="ru">Broome J.D. Antilymphoma activity of L-asparaginase in vivo: clearance rate of enzyme preparations from guinea-pig serum and yeast in relation of their effects on tumor growth. J Natl Acad Sci U S A 1965;35:967—74.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5.	Yellin T.O., Wriston J.C. Purification and properties of guinea-pig serum asparaginase. Biochemistry 1966;5:1605—12.</mixed-citation><mixed-citation xml:lang="ru">Yellin T.O., Wriston J.C. Purification and properties of guinea-pig serum asparaginase. Biochemistry 1966;5:1605—12.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6.	Mashburn L.T., Wriston J.C. Tumor inhibitory effect of L-asparaginase from Escherichia coli. Arch Biochem Biophys 1964;105:451—2.</mixed-citation><mixed-citation xml:lang="ru">Mashburn L.T., Wriston J.C. Tumor inhibitory effect of L-asparaginase from Escherichia coli. Arch Biochem Biophys 1964;105:451—2.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7.	Asselin B.L., Whitin J.C., Coppola D.J. et al. Compartive pharmacokinetic studies of three aspsraginase preparation. J Clin Oncol 1993;11:1780—6.</mixed-citation><mixed-citation xml:lang="ru">Asselin B.L., Whitin J.C., Coppola D.J. et al. Compartive pharmacokinetic studies of three aspsraginase preparation. J Clin Oncol 1993;11:1780—6.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8.	Khan A., Hill J.M. Atopic hypersensitivity to L-asparaginase: resistance to immunosuppression. Int Arch Allergy Appl Immunol 1971;40(3):463—569.</mixed-citation><mixed-citation xml:lang="ru">Khan A., Hill J.M. Atopic hypersensitivity to L-asparaginase: resistance to immunosuppression. Int Arch Allergy Appl Immunol 1971;40(3):463—569.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9.	Ertel I.J., Nesbit M.E., Hammond D. et al. Effective dose of L-asparaginase for induction of remission in previously treated children with acute lymphoblastic leukemia: a report from Childrens Cancer Study Group. Cancer Res 1979;39(10):3893—6.</mixed-citation><mixed-citation xml:lang="ru">Ertel I.J., Nesbit M.E., Hammond D. et al. Effective dose of L-asparaginase for induction of remission in previously treated children with acute lymphoblastic leukemia: a report from Childrens Cancer Study Group. Cancer Res 1979;39(10):3893—6.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10.	Albertsen B.K., Schroder H., Ingerslev J. et al. Comparison of intramuscular therapy with Erwinia asparaginase and asparag-ibase Medac: pharmacokinetics pharmacodynamics, formation of antibodies and influence on coagulation system. Br J Hematol 2001;96(5):983—90.</mixed-citation><mixed-citation xml:lang="ru">Albertsen B.K., Schroder H., Ingerslev J. et al. Comparison of intramuscular therapy with Erwinia asparaginase and asparag-ibase Medac: pharmacokinetics pharmacodynamics, formation of antibodies and influence on coagulation system. Br J Hematol 2001;96(5):983—90.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11.	Albertsen B.K., Jacibsen P., Schroder H. et al. Pharmacokinetics of Erwinia asparaginase after intravenous and intramuscular administration. Cancer Chemither Pharmacol 2001;48(1):77—82.</mixed-citation><mixed-citation xml:lang="ru">Albertsen B.K., Jacibsen P., Schroder H. et al. Pharmacokinetics of Erwinia asparaginase after intravenous and intramuscular administration. Cancer Chemither Pharmacol 2001;48(1):77—82.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12.	Albertsen B.K., Schroder H., Jacibsen P. et al. Monitoring of Erwinia asparaginase therapy in childhood ALL in the Nordic countries. Br J Clin Pharmaco 2001;52:433—7.</mixed-citation><mixed-citation xml:lang="ru">Albertsen B.K., Schroder H., Jacibsen P. et al. Monitoring of Erwinia asparaginase therapy in childhood ALL in the Nordic countries. Br J Clin Pharmaco 2001;52:433—7.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13.	Sallan S.E., Hitchcock-Bryan S. Gelberg R. et al. Influence of intensive asparaginase in treatment of childhood non-T-cell acute lymphoblastic leukemia. Cancer Res 1983;43(11):5601—7.</mixed-citation><mixed-citation xml:lang="ru">Sallan S.E., Hitchcock-Bryan S. Gelberg R. et al. Influence of intensive asparaginase in treatment of childhood non-T-cell acute lymphoblastic leukemia. Cancer Res 1983;43(11):5601—7.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14.	Abshire T.C., Pollock B.H., Billet A.L. et al. Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia leukemia: a Pediatric Oncology Group Study. Blood 2000;96(5):1709—15.</mixed-citation><mixed-citation xml:lang="ru">Abshire T.C., Pollock B.H., Billet A.L. et al. Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia leukemia: a Pediatric Oncology Group Study. Blood 2000;96(5):1709—15.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15.	Hawkims D.S., Park J.R., Thomson B.G. et al. Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase for children with relapsed acute lymphoblastic leukemia. Clin Cancer Res 2004;10(16):5335—41.</mixed-citation><mixed-citation xml:lang="ru">Hawkims D.S., Park J.R., Thomson B.G. et al. Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase for children with relapsed acute lymphoblastic leukemia. Clin Cancer Res 2004;10(16):5335—41.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16.	Holcenger J.S., Teller D.C. Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A. J Biol Chem 1976;251(17):5375—80.</mixed-citation><mixed-citation xml:lang="ru">Holcenger J.S., Teller D.C. Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A. J Biol Chem 1976;251(17):5375—80.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17.	Avramis V.I., Sencer S., Periclou A.P. et al. Randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children’s Cancer Study Group. Blood 2002;99(6):1986—94.</mixed-citation><mixed-citation xml:lang="ru">Avramis V.I., Sencer S., Periclou A.P. et al. Randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children’s Cancer Study Group. Blood 2002;99(6):1986—94.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18.	Panosyan E.H., Seibel N.L., Gaynon P.S. et al. Asparaginase antibody and asparaginase activity in childhood in higher risk acute lymphoblastic leukemia: Children’s Cancer Group Study CCG-1961. J Pediatr Hematol Oncol 2004;26(4):217—26.</mixed-citation><mixed-citation xml:lang="ru">Panosyan E.H., Seibel N.L., Gaynon P.S. et al. Asparaginase antibody and asparaginase activity in childhood in higher risk acute lymphoblastic leukemia: Children’s Cancer Group Study CCG-1961. J Pediatr Hematol Oncol 2004;26(4):217—26.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19.	Asselin B.L., Whitin J.C., Coppola D.J. et al. Comparative pharmacokinetic studies of three asparaginase preparations. J Clin Oncol 1993;11(9):1780—6.</mixed-citation><mixed-citation xml:lang="ru">Asselin B.L., Whitin J.C., Coppola D.J. et al. Comparative pharmacokinetic studies of three asparaginase preparations. J Clin Oncol 1993;11(9):1780—6.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20.	Boos J., Werber G., Ahlke E. et al. Monitoring of asparaginase activity and asparagine levels in children with different asparaginase preparations. Eur J Cancer 1996;32A(9):544—50.</mixed-citation><mixed-citation xml:lang="ru">Boos J., Werber G., Ahlke E. et al. Monitoring of asparaginase activity and asparagine levels in children with different asparaginase preparations. Eur J Cancer 1996;32A(9):544—50.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21.	Ahlke E., Nowak-Gottl U., Schultze-Westhoff P. et al. Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukemia. Br J Hematol 1997;96:675-81.</mixed-citation><mixed-citation xml:lang="ru">Ahlke E., Nowak-Gottl U., Schultze-Westhoff P. et al. Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukemia. Br J Hematol 1997;96:675-81.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">22.	Muller H.J., Loning L., Horn A. et al. Pegilated asparaginase (OncasparTM) in children with ALL: drug monitoring in reinduction according to the ALL/NHL-BFM 95 protocols. Br J Hematol 2000;110:379-84.</mixed-citation><mixed-citation xml:lang="ru">Muller H.J., Loning L., Horn A. et al. Pegilated asparaginase (OncasparTM) in children with ALL: drug monitoring in reinduction according to the ALL/NHL-BFM 95 protocols. Br J Hematol 2000;110:379-84.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">23.	Vieira Pinherio J.P., Ahlke E., Nowak-Gottl U. et al. Pharmacokinetic of dose adjustment of Erwinia asparaginase in protocol II of the pediatric ALL/NHL-BFM treatment protocols. Br J Hematol 1999;104:313-20.</mixed-citation><mixed-citation xml:lang="ru">Vieira Pinherio J.P., Ahlke E., Nowak-Gottl U. et al. Pharmacokinetic of dose adjustment of Erwinia asparaginase in protocol II of the pediatric ALL/NHL-BFM treatment protocols. Br J Hematol 1999;104:313-20.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">24.	Vieira Pinherio J.P., Muller H.J., Schwabe D. et al. Drug monitoring of low dose PEG-asparaginase (Oncaspar™) in children with relapsed acute lymphoblastic leukemia (ALL). Br J Hematol 2001;113:115-9.</mixed-citation><mixed-citation xml:lang="ru">Vieira Pinherio J.P., Muller H.J., Schwabe D. et al. Drug monitoring of low dose PEG-asparaginase (Oncaspar™) in children with relapsed acute lymphoblastic leukemia (ALL). Br J Hematol 2001;113:115-9.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">25.	Muller H.J., Beier R., da Palma J.C. et al. PI^G-asparaginase (Oncaspar™) 2,500 U/m BSA in re-induction and relapse treatment of the ALL/NHL-BFM protocols. Cancer Chemother Pharmacol 2002;49:149-54.</mixed-citation><mixed-citation xml:lang="ru">Muller H.J., Beier R., da Palma J.C. et al. PI^G-asparaginase (Oncaspar™) 2,500 U/m BSA in re-induction and relapse treatment of the ALL/NHL-BFM protocols. Cancer Chemother Pharmacol 2002;49:149-54.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">26.	Gaynon P.S., Harris R.E., Stram S.O. et al. Asparagine (ASN) depletion and treatment response in chikdhood acute lymphoblastic leukemia (ALL) after an early marrow relapse: a Children’s Cancer Group trial (CCG-1941) [abstract]. Blood 1999;94(10 Suppl 1):628a.</mixed-citation><mixed-citation xml:lang="ru">Gaynon P.S., Harris R.E., Stram S.O. et al. Asparagine (ASN) depletion and treatment response in chikdhood acute lymphoblastic leukemia (ALL) after an early marrow relapse: a Children’s Cancer Group trial (CCG-1941) [abstract]. Blood 1999;94(10 Suppl 1):628a.</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">27.	Panosyan E., Avramis I.A., Seibel N.L. et al. Glutamine (Gln) deamonation by asparaginases (ASNases) in children with high risk acute lymphoblastic leukemia (HR ALL), (CCG-1961 study) [abstract]. Blood 2002;100:759A.</mixed-citation><mixed-citation xml:lang="ru">Panosyan E., Avramis I.A., Seibel N.L. et al. Glutamine (Gln) deamonation by asparaginases (ASNases) in children with high risk acute lymphoblastic leukemia (HR ALL), (CCG-1961 study) [abstract]. Blood 2002;100:759A.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">28.	Avramis V.I., Panosyan E.H. Pharmacokinetic/Pharmacodynamic relations of asparaginase formulations the past, the present and recommendations for the future. Clin Pharmacokokinet 2005;44(4):367-93.</mixed-citation><mixed-citation xml:lang="ru">Avramis V.I., Panosyan E.H. Pharmacokinetic/Pharmacodynamic relations of asparaginase formulations the past, the present and recommendations for the future. Clin Pharmacokokinet 2005;44(4):367-93.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">29.	Vieira Pinherio J.P., Wenner K., Escherich G. et al. Serum asparaginase activities and asparagine concentrations in the cerebrospinal fluid after a single infusion of 2,500 U/m PEG asparaginase in children with ALL treated according to protocol COALL-06-97. Pediatr Blood Cancer 2006;46:18-25.</mixed-citation><mixed-citation xml:lang="ru">Vieira Pinherio J.P., Wenner K., Escherich G. et al. Serum asparaginase activities and asparagine concentrations in the cerebrospinal fluid after a single infusion of 2,500 U/m PEG asparaginase in children with ALL treated according to protocol COALL-06-97. Pediatr Blood Cancer 2006;46:18-25.</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">30.	Rizzari C., Zucchetti M., Conter V. et al. L-Asparagine depletion and L-asparag-inase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C or E. coli L-asparaginase as the first exposure. Ann Oncol 2000;11(2):189-93.</mixed-citation><mixed-citation xml:lang="ru">Rizzari C., Zucchetti M., Conter V. et al. L-Asparagine depletion and L-asparag-inase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C or E. coli L-asparaginase as the first exposure. Ann Oncol 2000;11(2):189-93.</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">31.	Avramis V.I., Senser S., Periclou A.P. et al. A randomized comparison of native Escherichia coli aspsraginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard risk acute lymphoblastic leukemia: a Children’s Cancer Group study. Blood 2002;99:1986-94.</mixed-citation><mixed-citation xml:lang="ru">Avramis V.I., Senser S., Periclou A.P. et al. A randomized comparison of native Escherichia coli aspsraginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard risk acute lymphoblastic leukemia: a Children’s Cancer Group study. Blood 2002;99:1986-94.</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">32.	Appel I.M., Pinheiro JPV., den Boer M.K. et al. Lack of asparagines depletion in the ceredrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL. Leukemia 2003;17:2254-6.</mixed-citation><mixed-citation xml:lang="ru">Appel I.M., Pinheiro JPV., den Boer M.K. et al. Lack of asparagines depletion in the ceredrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL. Leukemia 2003;17:2254-6.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
