OncohematologyOncohematologyОнкогематология1818-83462413-4023Publishing House ABV Press5010.17650/1818-8346-2012-7-3-22-29HEMATOLOGIC MALIGNANCIES: DIAGNOSIS, TREATMENT, SUPPORTIVE CAREГЕМОБЛАСТОЗЫ: ДИАГНОСТИКА, ЛЕЧЕНИЕ, СОПРОВОДИТЕЛЬНАЯ ТЕРАПИЯPathogenesis and therapy of anemia in oncohemathology patients with recombinant erythropoietin agents (review)Патогенез и терапия анемии препаратами рекомбинантного эритропоэтина у онкогематологических больных (обзор современной литературы)RomanenkoN. A.РоманенкоН. А.
Russian Federation
rom-nik@yandex.ruRussian Research Institute of Hematology and Transfusiology, Russian Federal Medico‑biological AgencyФГБУ «Российский научно‑исследовательский институт гематологии и трансфузиологии» ФМБА России2208201273222922072014220720142012https://oncohematology.abvpress.ru/ongm/article/view/50

The article presents a literature review on the mechanisms of anemia in patients with hematologic malignancies and a classification of chronic anemia and methods of its correction. It describes in detail the mechanism of action, indications and side effects of rembinant erythropoietin (rEPO). It gives anemia treatment algorithms with rEPO in patients with chronic blood malignancies. The analysis of rEPO efficacy is shown in anemia treatment in patients with various types of cancer. It presents the recommendations of ASCO/ASH for the use of rEPO in various patients categories.

В статье представлен обзор литературы по механизмам развития анемии у больных онкогематологическими заболеваниями. Приведена классификация хронической анемии и методы ее коррекции. Подробно описаны механизмы действия, показания и побочные эффекты препаратов рекомбинантного эритропоэтина (рЭПО). Приведены алгоритмы лечения хронической анемии у пациентов с опухолевыми заболеваниями системы крови с помощью препаратов рЭПО. Представлен анализ эффективности препаратов рЭПО, используемых для терапии анемии у больных различными видами онкологических заболеваний. Представлены рекомендации ASCO/ASH по применению препаратов рЭПО у различных категорий больных.

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