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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Oncohematology</journal-id><journal-title-group><journal-title xml:lang="en">Oncohematology</journal-title><trans-title-group xml:lang="ru"><trans-title>Онкогематология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8346</issn><issn publication-format="electronic">2413-4023</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">436</article-id><article-id pub-id-type="doi">10.17650/1818-8346-2020-15-3-107-127</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>SUPPORTIVE THERAPY ASPECTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АСПЕКТЫ ПОДДЕРЖИВАЮЩЕЙ ТЕРАПИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Possibilities of supportive therapy in patients with blood system tumors and malignant neoplasms</article-title><trans-title-group xml:lang="ru"><trans-title>Возможности поддерживающей терапии при опухолях системы крови и у пациентов со злокачественными новообразованиями</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4614-606X</contrib-id><name-alternatives><name xml:lang="en"><surname>Larionova</surname><given-names>V. B.</given-names></name><name xml:lang="ru"><surname>Ларионова</surname><given-names>В. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>24 Kashirskoe Shosse, Moscow 115478, Russia</italic></p></bio><bio xml:lang="ru"><p><bold>Вера Борисовна Ларионова</bold></p><p><italic>Россия, 115478 Москва, Каширское шоссе, 24</italic></p></bio><email>larionova1951@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0170-5681</contrib-id><name-alternatives><name xml:lang="en"><surname>Snegovoy</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Снеговой</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>24 Kashirskoe Shosse, Moscow 115478, Russia</italic></p></bio><bio xml:lang="ru"><p><italic>Россия, 115478 Москва, Каширское шоссе, 24</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-16" publication-format="electronic"><day>16</day><month>10</month><year>2020</year></pub-date><volume>15</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>107</fpage><lpage>127</lpage><history><date date-type="received" iso-8601-date="2020-10-15"><day>15</day><month>10</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-10-15"><day>15</day><month>10</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://oncohematology.abvpress.ru/ongm/article/view/436">https://oncohematology.abvpress.ru/ongm/article/view/436</self-uri><abstract xml:lang="en"><p>Finding opportunities to improve treatment outcomes of cancer patients remains a difficult and unresolved problem. Modern anticancer treatment due to the intensity and molecular biological orientation allows achieving higher efficiency and theoretically reducing the complications frequency. At the same time, the “increase in efficiency” in the modern oncology really exists, but a “decrease in the incidence of complications” is far from its solution. In many ways, the problems of diagnosis, treatment and monitoring of complications are associated with the impact on complex physiological processes in the body of an oncological patient. Timely implementation of modern and adequate programs for the prevention and treatment of these complications defines the concept of “supportive therapy”, which provides at least half of the effectiveness of anticancer treatment.</p><p>The Multinational Association of Supportive Care in Cancer (MASCC) was formed in 1990. The main tasks of the association were the creation of supportive care system, its popularization and accumulation of scientific data. The MASCC was used not only oncologists experience, but also of specialists working in almost all areas of medicine. Supportive therapy provides prevention and treatment of complications from the moment of malignant disease develops, at all stages of anticancer treatment, during the rehabilitation period, and in patients in the terminal phase.</p><p>An important stage in the development of maintenance care in Russia was the holding of annual conferences in Moscow with the support of MASCC. Russia is included in the European MASCC group and in working group on supportive therapy and palliative care of the Chemotherapists Society (ESMO). The Russian Society of Supportive care in Oncology (RASSC) was organized In Russia on June 1, 2017. In recent years, the main directions of supportive care have been developed in our country. Today, supportive therapy is an obligatory component of anticancer programs, which allows the patient to cope with severe but potentially reversible disorders of vital organs at all stages of treatment. This is a real way to increase the treatment efficacy and improve the quality of life of cancer patients.</p></abstract><trans-abstract xml:lang="ru"><p>Поиск путей улучшения результатов лечения онкологических больных остается трудной и до конца не решенной задачей. Современное противоопухолевое лечение за счет интенсивности и молекулярно-биологической направленности позволяет добиться более высокой эффективности и теоретически снизить частоту осложнений. При этом «повышение эффективности» в современной онкологии действительно существует, но «снижение частоты осложнений» далеко от своего решения. Во многом проблемы диагностики, лечения и мониторинга осложнений связаны с воздействием на сложные физиологические процессы, протекающие в организме онкологического больного. Своевременное проведение современных и адекватных программ профилактики и лечения этих осложнений определяет понятие «поддерживающая терапия», которая обеспечивает не менее половины эффективности противоопухолевого лечения.</p><p>В 1990 г. была организована Международная ассоциация по поддерживающей терапии в онкологии (Multinational Association of Supportive Care in Cancer, MASCC). Основными задачами ассоциации стали создание системы поддерживающей терапии, ее популяризация, накопление научного материала по данному разделу. В работе MASCC использовали опыт не только онкологов, но и специалистов, работающих практически во всех областях медицины. Поддерживающая терапия обеспечивает профилактику и лечение осложнений, возникающих при развитии злокачественного заболевания, на всех этапах противоопухолевого лечения, в период реабилитации, а также у пациентов в терминальной фазе.</p><p>Важным этапом в развитии поддерживающей терапии в России стало проведение ежегодных конференций в г. Москве при поддержке MASCC. Россия включена в европейскую группу MASCC и состав рабочей группы по поддерживающей терапии и паллиативной помощи общества химиотерапевтов (ESMO). В России 1 июня 2017 г. было создано Общество специалистов поддерживающей терапии в онкологии (Russian Society of Supportive care in Oncology, RASSC). В течение последних лет в нашей стране разработаны основные направления поддерживающей терапии. Сегодня поддерживающая терапия является обязательной составляющей противоопухолевых программ, что позволяет пациенту на всех этапах лечения справиться с тяжелыми, но потенциально обратимыми расстройствами жизненно важных органов. Это реальный путь к повышению эффективности лечения и улучшению качества жизни онкологических пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stage of organization and development of supportive care</kwd><kwd>cluster classification of anticancer treatment complications</kwd><kwd>toxicity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>этап создания и развития поддерживающей терапии</kwd><kwd>кластерная классификация осложнений противоопухолевого лечения</kwd><kwd>токсичность</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Roé E., García Muret M.P., Marcuello E. et al. Description and management of cutaneous side effects during cetuximab or erlotinib treatments: a prospective study of 30 patient. J Am Acad Dermatol 2006;55(3):429–37. DOI: 10.1016/j.jaad.2006.04.062.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Herrstedt J. 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