OncohematologyOncohematologyОнкогематология1818-83462413-4023Publishing House ABV Press12510.17650/1818-8346-2014-9-3-67-71EDUCATIONAL LECTURES, REVIEWSОБРАЗОВАТЕЛЬНЫЕ ЛЕКЦИИ, ОБЗОРЫBasic mechanisms of iron metabolism regulation and their clinical significanceОсновные механизмы регуляции обмена железа и их клиническое значениеMeshсheryakovaL. M.МещеряковаЛ. М.
Russian Federation
ludmilagem@mail.ruLevinaA. A.ЛевинаА. А.
Russian Federation
TsybulskayaM. M.ЦыбульскаяМ. М.
Russian Federation
SokolovaT. V.СоколоваТ. В.
Russian Federation
Hematologic Scientific Center, Ministry of Health of Russia, MoscowФГБУ ГНЦ Минздрава России, МоскваOutpatient center “City polyclinic № 62”, Moscow Department of Health CareАмбулаторный центр ГБУЗ «Городская поликлиника № 62» Департамента здравоохранения г. Москвы3010201493677130012015300120152014https://oncohematology.abvpress.ru/ongm/article/view/125

This article is а composition of literature and experimental data of iron metabolism. There were studied the level of DMT-1, ferroportin, hepcidin at different stages of anemia and hemochromatosis. It is clear that the level of DMT-1 regulates by the hepcidin. Increaseing of the hepcidin concentration and decreasing DMT-1 level in patients with hemochromatosis explained good results of treatment.

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