OncohematologyOncohematologyОнкогематология1818-83462413-4023Publishing House ABV Press105610.17650/1818-8346-2025-20-3-84-96SUPPORTIVE THERAPY ASPECTSАСПЕКТЫ ПОДДЕРЖИВАЮЩЕЙ ТЕРАПИИInvasive fungal diseases in recipients of allogeneic hematopoietic stem cells: current state of the problemИнвазивные микозы у реципиентов аллогенных гемопоэтических стволовых клеток: современное состояние проблемыhttps://orcid.org/0000-0001-9230-6960MironovaD. A.МироноваД. А.
Russian Federation

Daria Aleksandrovna Mironova

4 Novyy Zykovskiy Proezd, Moscow 125167

Дарья Александровна Миронова

125167 Москва, Новый Зыковский пр-д, 4

mrnvdaria@gmail.comhttps://orcid.org/0000-0001-6201-6276KuzminaL. A.КузьминаЛ. А.
Russian Federation

4 Novyy Zykovskiy Proezd, Moscow 125167

125167 Москва, Новый Зыковский пр-д, 4

https://orcid.org/0000-0001-5973-5763KlyasovaG. A.КлясоваГ. А.
Russian Federation

4 Novyy Zykovskiy Proezd, Moscow 125167

125167 Москва, Новый Зыковский пр-д, 4

National Medical Research Center for Hematology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр гематологии» Минздрава России1109202520384961109202511092025https://oncohematology.abvpress.ru/ongm/article/view/1056

Allogeneic hematopoietic stem cell transplantation is a standard treatment option for a variety of hematological disorders. In recent years, there has been observed an increase in transplantation activity worldwide as well as in use of alternative donors. Despite introduction of antifungal prophylaxis, recipients of allogeneic hematopoietic stem cells still have a high risk of invasive fungal disease.This review represents risk factors, frequency and structure of invasive fungal disease in this category of patients.

Трансплантация аллогенных гемопоэтических стволовых клеток – непременная составляющая лечения ряда гематологических заболеваний. За последние годы отмечаются рост трансплантационной активности по всему миру, увеличение доли альтернативных доноров. Несмотря на противогрибковую профилактику, у реципиентов аллогенных гемопоэтических стволовых клеток сохраняется высокий риск развития инвазивного микоза.В обзоре представлено современное состояние проблемы по факторам риска, частоте и структуре инвазивных микозов у этой категории больных.

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