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Clinical case of giant extramedullar plasmacytoma in a patient with multiple myeloma
- Authors: Safuanova G.S.1, Mansurova Y.R.1, Latypova A.A.2, Bagautdinova А.U.2, Rozhenkova T.Y.2, Valiakhmetova C.K.2
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Affiliations:
- Bashkir State Medical University, Ministry of Health of Russia
- G.G. Kuvatov Republican Clinical Hospital
- Issue: Vol 18, No 4 (2023)
- Pages: 58-63
- Section: HEMATOLOGIC MALIGNANCIES: TREATMENT
- Published: 07.12.2023
- URL: https://oncohematology.abvpress.ru/ongm/article/view/867
- DOI: https://doi.org/10.17650/1818-8346-2023-18-4-58-63
- ID: 867
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Abstract
One possible manifestation of multiple myeloma may be extramedullary plasmacytoma, manifested by infiltration of plasma cells outside the bone marrow. In the debut of the disease, bone plasmacytomas are most often diagnosed, in contrast to extramedullary ones, which are rare. According to the literature, the presence of extramedullary plasmacytoma is an unfavorable factor characterized by an aggressive disease course, the absence of an antitumor response to standard therapy, and low overall survival rates. Therefore, the pathogenesis, clinic, diagnosis and treatment of this variant of the disease require additional study. This article presents a clinical case of an aggressive course of extensive extramedullary plasmacytoma in a patient with multiple myeloma with an assessment of various combination therapy regimens efficacy.
About the authors
G. Sh. Safuanova
Bashkir State Medical University, Ministry of Health of Russia
Author for correspondence.
Email: safuanova@bk.ru
ORCID iD: 0000-0003-2627-0626
Guzyal Sh. Safuanova
3 Lenina St., Ufa 450008
Russian FederationYu. R. Mansurova
Bashkir State Medical University, Ministry of Health of Russia
ORCID iD: 0000-0002-4503-8200
3 Lenina St., Ufa 450008
Russian FederationA. A. Latypova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0000-0002-9508-3878
132 Dostoevskogo St., Ufa 450005
Russian FederationА. U. Bagautdinova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0000-0002-7021-7470
132 Dostoevskogo St., Ufa 450005
Russian FederationT. Yu. Rozhenkova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0009-0009-1956-3034
132 Dostoevskogo St., Ufa 450005
Russian FederationCh. Kh. Valiakhmetova
G.G. Kuvatov Republican Clinical Hospital
ORCID iD: 0009-0000-7156-7280
132 Dostoevskogo St., Ufa 450005
Russian FederationReferences
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