Comparative efficacy of acute lymphoblastic leukemia treatment of children in St.-Petersburg using two COALL-92 versions

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Abstract

Treatment results in children with acute lymphoblastic leukemia (ALL) treating in St.-Petersburg hospitals according to two modified version of German protocol CO ALL-92 from 01.01.1993 to 01.01.2007 are presented. 438 primary A LL patients aged from 4 months to 17 year s have been included in the study . ALL diagnosed according to international criteria. Based on prognostic factors patients were a llocated to one of two risk groups, which determined therapy intensity . The total treatment duration in both groups w as 2 years and consist ed of 5.5–8 months intensive phase with subsequent maintenance therapy . A comparative treatment results analysis in children with A LL according to two modified versions of COALL-92 is presented.

About the authors

E. G. Boychenko

Municipal Children Hospital № 1

Author for correspondence.
Email: boychenko-elmira@yandex.ru
Отделение химиотерапии лейкозов Russian Federation

E. M. Petrova

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

I. A. Garbuzova

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

E. A. Nikitina

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

L. M. Shchugareva

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

T. N. Kulakova

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

T. A. Makarova

Municipal Children Hospital № 1

Отделение химиотерапии лейкозов Russian Federation

M. B. Belogurova

Municipal Clinical Hospital № 31

отделение детской онкологии и гематологии Russian Federation

G. G. Radulesku

Municipal Clinical Hospital № 31

отделение детской онкологии и гематологии Russian Federation

T. D. Viktorovich

Municipal Clinical Hospital № 31

отделение детской онкологии и гематологии Russian Federation

E. D. Chavpetsova

Городская больница № 31

Municipal Clinical Hospital № 31 Russian Federation

L. I. Shats

Municipal Clinical Hospital № 31

отделение детской онкологии и гематологии Russian Federation

G. I. Uleyskaya

Municipal Clinical Hospital № 31

отделение детской онкологии и гематологии Russian Federation

I. S. Martynkevich

Russian Research Institute of Hematology and Transfusiology

Russian Federation

E. E. Zueva

Saint-Petersburg Pavlov State Medical University

Russian Federation

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