Mesenchymal stem cells biological properties and possibilities of clinical use

O. S. Tatarinova; Татаринова О. С.; E. Yu. Osipova; Осипова Е. Ю.; S. A. Roumiantsev; Румянцев С. А.

doi:10.17650/1818-8346-2009-0-4-33-44

Mesenchymal stem cells biological properties and possibilities of clinical use

Authors: Tatarinova O.S.¹, Osipova E.Y.², Roumiantsev S.A.²
Affiliations:
1. Lomonosov Moscow state university
2. Federal research center of pediatric hematology, oncology and immunology
Issue: No 4 (2009)
Pages: 33-44
Section: ФУНДАМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ
Published: 28.11.2009
URL: https://oncohematology.abvpress.ru/ongm/article/view/784
DOI: https://doi.org/10.17650/1818-8346-2009-0-4-33-44
ID: 784

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Abstract

Autologic and allogeneic mesenchymal stem cells (MSC) transplantation currently is used in clinical practice for hematopoietic progenitor engraftment acceleration and graft versus host disease prophylactic and treatment. In this literature review data concerning efficacy, safety and technologies of MSC clinical use are analyzed. Biological properties of MSC received in long-term culture and mechanisms of their interaction with other cells are discussed.