Primary lymphatic tumors of bones: two case reports and a review of literature

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Abstract

Primary bone lymphoma (PBL) is a rare disease. In this article two cases of primary diffuse large B-cell lymphoma of bones are described, one case of solitary lesion and the other of multiple lesions. Both patients were treated with courses CHOEP in combination with radiotherapy and achieved a complete remission (CR). The patient with solitary lesion is still in CR with the follow-up of 33 months. The patient with multiple lesions where partial remission has been received died in 3 months after the end of therapy from disease progression. The authors discuss differential diagnosis and present a review of literature concerning PBL.

About the authors

E. K. Egorova

Hematological Research Center, Russian Academy of Medical Sciences

Author for correspondence.

Moscow

Russian Federation

N. G. Gabeeva

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

V. Ye. Mamonov

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

D. S. Maryin

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

I. B. Kaplanskaya

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

E. E. Zvonkov

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

A. U. Magomedova

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

S. K. Kravchenko

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

A. M. Kremenestskaya

Hematological Research Center, Russian Academy of Medical Sciences

Moscow

Russian Federation

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