Hemostasis defects correction in children with acute lymphoblastic leukemia

   Last years an insufficient attention is given to one of the frequent and serious syndromes accompanying children acute lymphoblastic leukemia (ALL) — hemorrhagic syndrome. Hemostasis correction in children with ALL is poorly differentiated owing to absence of timely hemostasis defects diagnostics. In our study heterogeneity of hemostasis defects in children with ALL received polychemotherapy according to ALL-BFM-90 protocol has been established which allows pathogenetic correction of these defects for the prophylactics and treatment of hemorrhagic and trombotic complications.