New approaches for combined therapy of Hodgkin's lymphoma

P. V. Dacenko; Даценко П. В.; G. A. Panshin; Паньшин Г. А.; V. M. Sotnikov; Сотников В. М.; Y. D. Melnik; Мельник Ю. Д.; A. V. Ivashin; Ивашин А. В.; P. N. Podolsky; Подольский П. Н.

doi:10.17650/1818-8346-2007-0-4-27-35

New approaches for combined therapy of Hodgkin's lymphoma

Authors: Dacenko P.V.¹, Panshin G.A.¹, Sotnikov V.M.¹, Melnik Y.D.¹, Ivashin A.V.¹, Podolsky P.N.¹
Affiliations:
1. Russian Scientific Roentgen radiological Center, Ministry of Health Russian Federation
Issue: No 4 (2007)
Pages: 27-35
Section: THERAPY OF HEMATOLOGIC MALIGNANCIES
Published: 23.11.2007
URL: https://oncohematology.abvpress.ru/ongm/article/view/671
DOI: https://doi.org/10.17650/1818-8346-2007-0-4-27-35
ID: 671

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Abstract

Based on the treatment results of 819 patients we formulated new approaches for combined treatment of Hodgkin’s lymphoma stages I-IV. It was constructed a simplified prognostic model and developed new alternating chemotherapy regimens. We demonstrated the possibility of reducing the number of courses of chemotherapy to 4 in poor prognosis cases and the dispensability of achieving a complete effect after execution of medication period, emphasized the important role of a subradical programme, the expediency of zonal reduction offields, and the necessity of irradiating the whole volume of a lymphatic collector in the doses not greater than 30 Gy.

The above approaches offer prospects for treatment of Hodgkin’s lymphoma.