Paraneoplastic pemphigus - a rare autoimmune complication in patients with chronic lymphocytic leukemia

M. A. Volkova; Волкова М. А.; M. Yu. Kitchigina; Кичигина М. Ю.; N. S. Potekaev; Потекаев Н. С.; N. P. Teplyuk; Теплюк Н. П.; A. G. Kupriyanova; Куприянова А. Г.

doi:10.17650/1818-8346-2007-0-1-24-30

Paraneoplastic pemphigus - a rare autoimmune complication in patients with chronic lymphocytic leukemia

Authors: Volkova M.A.¹, Kitchigina M.Y.¹, Potekaev N.S.², Teplyuk N.P.², Kupriyanova A.G.³
Affiliations:
1. N.N. Blokhin Russian Cancer Research Centre, Russian Academy of Medical Sciences
2. I.M. Sechenov Moscow Medical Academy
3. National Research Institute of Transplantology and Artificial Organs
Issue: No 1 (2007)
Pages: 24-30
Section: RARE AND DIFFICULT HEMATOLOGIC SYNDROMES
Published: 22.02.2007
URL: https://oncohematology.abvpress.ru/ongm/article/view/614
DOI: https://doi.org/10.17650/1818-8346-2007-0-1-24-30
ID: 614

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Abstract

This is a case report of the 64-year-old male patient who suffered of previously untreated chronic lymphocytic leukemia (CLL), and paraneoplastic pemphigus. He was treated with prednisolone, MabThera, chlorambucil and cyclophosphamide. The patient achieved remission of CLL, and all symptoms of paraneoplastic pemphigus disappeared. During the year after the treatment he has good performance status, and receives only low doses of chlorambucil and prednisolone.