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Malnutrition in remission of childhood cancers as assessed by bioelectric impedance analysis
- Authors: Konovalova M.V.1, Anisimova A.V.2, Vashura A.Y.1, Godina E.Z.2, Nikolaev D.V.3, Rudnev S.G.4, Starunova O.A.5, Khomyakova I.A.2, Tseytlin G.Y.1
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Affiliations:
- Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology
- Lomonosov Moscow State University, Research Institute and Museum of Antropology
- SRC Medass
- Institute of Numerical Mathematics, Russian Academy of Sciences
- Lomonosov Moscow State University
- Issue: Vol 7, No 2 (2012)
- Pages: 42-50
- Section: QUALITY OF LIFE AND FOLLOW-UP
- Published: 22.05.2012
- URL: https://oncohematology.abvpress.ru/ongm/article/view/61
- DOI: https://doi.org/10.17650/1818-8346-2012-7-2-42-50
- ID: 61
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Abstract
The results of our cross-sectional bioimpedance study of children aged 7–17 years cured of cancer during follow-up (patients’ group, n = 552, remission time range 0–15 years) and of age-matched healthy controls (n = 1,500) show significant intergroup differences in body height and body composition parameters. The most pronounced alterations in the patients’ group were observed in standardized values of phase angle reflecting a sharp decrease in the percentage of metabolically active body cell mass in fat-free mass. Malnutrition, judged from the prevalence of obesity and low phase angle, was observed in 52.7 % of our patients reaching a maximum of 76.8 % in a subgroup of children with CNS tumors. In view of known association that exists between malnutrition and reduced tolerance to chemotherapy, increased susceptibility to infections and adverse outcomes rate, we recommend using bioimpedance analysis in remission of childhood cancers in order to monitoring and timely correction of nutritional state as well as for prevention of delayed cardiovascular risks.
About the authors
M. V. Konovalova
Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and ImmunologyRussian Federation
A. V. Anisimova
Lomonosov Moscow State University, Research Institute and Museum of AntropologyRussian Federation
A. Yu. Vashura
Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and ImmunologyRussian Federation
E. Z. Godina
Lomonosov Moscow State University, Research Institute and Museum of AntropologyRussian Federation
D. V. Nikolaev
SRC MedassRussian Federation
S. G. Rudnev
Institute of Numerical Mathematics, Russian Academy of SciencesRussian Federation
O. A. Starunova
Lomonosov Moscow State UniversityFaculty of Computational Mathematics and Cybernetics Russian Federation
I. A. Khomyakova
Lomonosov Moscow State University, Research Institute and Museum of AntropologyRussian Federation
G. Ya. Tseytlin
Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology
Author for correspondence.
Email: GrigoryTs@yandex.ru
Russian Federation
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