Patients with primary myelofibrosis: treatment and quality of life

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Abstract

Primary myelofibrosis (PMF) is one of the diseases that cannot be cured using modern methods of conservative therapy. Therefore, treatment aimed at reducing PMF severity and improving patient’s quality of life. In this article, a comparative analysis of treatment response and quality of life depending on therapy using was shown. Partial remission rate at approximately the same level after α-interferon treatment (55.3 %) and after cytotoxic drug (48.8 %) was observed. Significant improvement in quality of life during α-interferon treatment was revealed.

About the authors

L. M. Meshcheryakova

Hematological Research Center

Author for correspondence.
Russian Federation

O. V. Porotkova

Regional Clinical Hospital № 1

Russian Federation

L. G. Kovaleva

Hematological Research Center

Russian Federation

L. Yu. Kolosova

Hematological Research Center

Russian Federation

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