Extramedular lesions of a small intestinum in acute myeloid leukemia: case report and literature review

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Abstract

Currently, the diagnosis of acute myeloid lekemia is based on the standards of morphological studies and immunophenotyping of the bone marrow. The manifestation of the disease can be accompanied by extramedullary lesions, which are difficult to verify. The article presents a case of diagnosis of acute myeloid lekemia in an elderly w oman, occurring with a leukemic lesion of the small in - testine. Morphological studies and immunophenotyping of small intestine biopsy revealed acute myeloid lekemia blast tumor cells. Difficulties of examination in such cases lead to late revealing of leukemic infiltrates of rare localization and significantly worsen the prognosis. 

About the authors

I. A. Dokshina

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0002-1447-0199
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

A. V. Lyanguzov

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0001-5509-5308
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

S. V. Ignatyev

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

Author for correspondence.
Email: feb74@yandex.ru
ORCID iD: 0000-0002-8457-2967
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

O. Yu. Sergunina

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0003-4056-1323
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

S. L. Kalinina

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0002-5775-3471
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

E. S. Prokopyev

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0002-8952-1771
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

D. A. Dyakonov

Kirov Research Institute of Haematology and Blood Transfusion under the Federal Medicobiological Agency

ORCID iD: 0000-0001-8688-1344
72 Krasnoarmeyskaya St., Kirov 610027, Russia Russian Federation

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