REACTIVE PLASMACYTOSIS AT THE ONSET OF ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA. CASE REPORT

N. G. Chernova; Чернова Н. Г.; M. N. Sinitsyna; Синицына М. Н.; A. M. Kovrigina; Ковригина А. М.; Y. V. Sidorova; Сидорова Ю. В.; I. V. Galtseva; Гальцева И. В.; S. A. Mar’ina; Марьина С. А.; V. N. Dvirnyk; Двирнык В. Н.; E. E. Zvonkov; Звонков Е. Е.

doi:10.17650/1818-8346-2017-12-4-28-33

REACTIVE PLASMACYTOSIS AT THE ONSET OF ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA. CASE REPORT

Authors: Chernova N.G.¹, Sinitsyna M.N.¹, Kovrigina A.M.¹, Sidorova Y.V.¹, Galtseva I.V.¹, Mar’ina S.A.¹, Dvirnyk V.N.¹, Zvonkov E.E.¹
Affiliations:
1. National Research Center for Hematology, Ministry of Health of Russia
Issue: Vol 12, No 4 (2017)
Pages: 28-33
Section: HEMATOLOGIC MALIGNANCIES: DIAGNOSIS, TREATMENT, SUPPORTIVE CARE
Published: 08.12.2017
URL: https://oncohematology.abvpress.ru/ongm/article/view/264
DOI: https://doi.org/10.17650/1818-8346-2017-12-4-28-33
ID: 264

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Abstract

Angioimmunoblastic T-cell lymphoma is a rare T-cell lymphoproliferative disease with generalized lymphadenopathy, hepatosplenomegaly, intoxication and polyclonal hypergammaglobulinemia. The persistence of plasma cells in peripheral blood can be a manifestation of both tumor and reactive processes. In our article, we described the case of angioimmunoblastic T-cell lymphoma with an increase in the number of peripheral blood plasma cells to 28 %, and in bone marrow to 9 %. The complex diagnostics, including plasma cells immunophenotyping, morphology of the lymph node biopsy and bone marrow samples, made it possible to verify the diagnosis of angioimmunoblastic T-cell lymphoma with polyclonal plasmacytosis.