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MORPHOLOGY AND DISTRIBUTION OF Α-NAPHTHYL BUTIRATE ESTERASE AND NAPHTHOL AS-D CHLOROACETATE ESTERASE IN NORMAL MYELOMONOCYTIC PRECURSORS STUDIED BY THE CELL MICROARRAY
- Authors: Fedyanina O.S.1,2, Zakirova A.O.1,2, Zadorozhnaya A.E.3, Kapranov N.M.2,4, Khvastunova A.N.1,2, Yadgarova P.A.3, Filatov А.V.5, Burova O.S.6, Ataullakhanov F.I.1,2,3, Kuznetsova S.А.1,2
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Affiliations:
- Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev
- Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
- M.V. Lomonosov Moscow State University
- Hematological Research Center
- National Research Center, Institute of Immunology of the Federal Medical-Biological Agency of Russia
- N.N. Blokhin Russian Cancer Research Center
- Issue: Vol 11, No 4 (2016)
- Pages: 74-79
- Section: BASIC RESEARCH
- Published: 03.12.2016
- URL: https://oncohematology.abvpress.ru/ongm/article/view/219
- DOI: https://doi.org/10.17650/1818-8346-2016-11-4-74-79
- ID: 219
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Abstract
Here we describe and qualitatively characterize the distribution of mononuclear cells isolated from bone marrow aspirate of healthy donors and sorted by their surface CD antigens on a cell microarray by morphology (for 11 donors) and by absence or presence of α-naphthyl butyrate esterase and naphthol AS-D chloroacetate esterase (for 9 donors). These data can be used as a reference for the diagnosis of acute myeloid leukemia using the cell microarray.
About the authors
O. S. Fedyanina
Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev;Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
1 Samory Mashela St., Moscow 117997; Build. 1, 38A Leninskiy Prospekt, Moscow 119991
Russian FederationA. O. Zakirova
Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev;Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
1 Samory Mashela St., Moscow 117997; Build. 1, 38A Leninskiy Prospekt, Moscow 119991
Russian FederationA. E. Zadorozhnaya
M.V. Lomonosov Moscow State University
1 Leninskie Gory, Moscow 119991
Russian FederationN. M. Kapranov
Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences;Hematological Research Center
Build. 1, 38A Leninskiy Prospekt, Moscow 119; 4a Novyy Zykovskiy Proezd, Moscow 125167
Russian FederationA. N. Khvastunova
Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev;Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
1 Samory Mashela St., Moscow 117997; Build. 1, 38A Leninskiy Prospekt, Moscow 1199
Russian FederationP. A. Yadgarova
M.V. Lomonosov Moscow State University
1 Leninskie Gory, Moscow 119991
Russian FederationА. V. Filatov
National Research Center, Institute of Immunology of the Federal Medical-Biological Agency of Russia24 Kashirskoe Shosse, Moscow 11547 Russian Federation
O. S. Burova
N.N. Blokhin Russian Cancer Research Center
23 Kashirskoe Shosse, Moscow 115478
Russian FederationF. I. Ataullakhanov
Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev;Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences;
M.V. Lomonosov Moscow State University
1 Samory Mashela St., Moscow 117997; Build. 1, 38A Leninskiy Prospekt, Moscow 11999;1 Leninskie Gory, Moscow 119991
Russian FederationS. А. Kuznetsova
Federal Research Centre of Pediatric Hematology, Oncology, and Immunology named after Dmitriy Rogachev;Center of Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
Author for correspondence.
Email: kuznetsova.sonya@gmail.com
1 Samory Mashela St., Moscow 117997; Build. 1, 38A Leninskiy Prospekt, Moscow 119991
Russian FederationReferences
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