Email this article 
Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports
- Authors: Zerkalenkova E.A.1, Illarionova O.I.1, Kazakova A.N.1, Ponomareva N.I.2, Baydun L.V.2, Osipova E.Y.1, Dubrovina M.E.1, Popov A.M.1, Konyukhova T.V.1, Plyasunova S.A.1, Myakova N.V.1, Maschan A.A.1, Olshanskaya Y.V.1
-
Affiliations:
- Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1
- Russian Children Clinical Hospital, 119571 Moscow, Leninskiy pr., 117
- Issue: Vol 11, No 2 (2016)
- Pages: 21-29
- Section: HEMATOLOGIC MALIGNANCIES: DIAGNOSIS, TREATMENT, SUPPORTIVE CARE
- Published: 04.08.2016
- URL: https://oncohematology.abvpress.ru/ongm/article/view/193
- DOI: https://doi.org/10.17650/1818-8346-2016-11-2-21-29
- ID: 193
Cite item
Full Text
Abstract
Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse.
About the authors
E. A. Zerkalenkova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1
Author for correspondence.
Email: eazerkalenkova@gmail.com
Russian Federation
O. I. Illarionova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
A. N. Kazakova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
N. I. Ponomareva
Russian Children Clinical Hospital, 119571 Moscow, Leninskiy pr., 117Russian Federation
L. V. Baydun
Russian Children Clinical Hospital, 119571 Moscow, Leninskiy pr., 117Russian Federation
E. Yu. Osipova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
M. E. Dubrovina
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
A. M. Popov
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
T. V. Konyukhova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
S. A. Plyasunova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
N. V. Myakova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
A. A. Maschan
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
Yu. V. Olshanskaya
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 117997 Moscow, Samory Mashela str., 1Russian Federation
References
Supplementary files
