Cardiovascular and metabolic problems associated with application of second generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia

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Abstract

During therapy with second generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia, a number of patients demonstrate non-hematological toxicity of various degrees. The article contains review of references about second generation tyrosine kinase inhibitors effect on the frequency of cardiovascular and metabolic problems.

About the authors

O. Y. Vinogradova

Federal Research Center of Pediatric Hematology, Oncology, and Immunology named after Dmitry Rogachev, Ministry of Health of Russia;
“N.I. Pirogov Russian National Research Medical University”, Ministry of Health of Russia

Author for correspondence.
Email: olgavinz@mail.ru

1 Samory Mashela St., Moscow, 117198;

1 Ostrovityanovа St., Moscow, 117997

Russian Federation

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