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Late non-infectious lung damage in children after allogeneic hematopoietic stem cells transplantation
- Authors: Skvortsova Y.V.1,2, Rudneva A.E.1,2, Delyagin V.M.1,2, Lerkhendorf Y.A.1,2, Tereshchenko G.V.1,2, Balashov D.N.1,2, Maschan M.A.1,2, Maschan A.A.1,2
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Affiliations:
- Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia
- 1 Samory Mashela St., Moscow, 117198, Russia
- Issue: Vol 10, No 1 (2015)
- Pages: 29-36
- Section: HEMATOPOIETIC STEM CELL TRANSPLANTATION
- Published: 04.06.2015
- URL: https://oncohematology.abvpress.ru/ongm/article/view/136
- DOI: https://doi.org/10.17650/1818-8346-2015-1-29-36
- ID: 136
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Abstract
Hematopoietic stem cells transplantation (HSCT) technology currently allows curing a lot of malignant and non-malignant diseases in adults and children. However, HSCT is highly toxic treatment. HSCT complications include the possibility of prolonged immunodeficiency, alloand autoimmune reactions and various organs dysfunction. These conditions require careful monitoring by specialists, early diagnosis and appropriate treatment. This article discusses the clinical features, diagnosis and treatment options of such late complications as non-infectious lung disease. These conditions can lead to disability of patients. Relevance and importance of timely diagnosis of these pathological conditions, including the range of clinical tests available on a residence, with a view to effective treatment can improve the quality of life of
children with complications after HSCT. Theoretical issues are illustrated by case report.
About the authors
Yu. V. Skvortsova
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, Russia
Author for correspondence.
Email: yuscvo@mail.ru
Russian Federation
A. E. Rudneva
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
V. M. Delyagin
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
Yu. A. Lerkhendorf
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
G. V. Tereshchenko
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
D. N. Balashov
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
M. A. Maschan
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
A. A. Maschan
Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117198, RussiaRussian Federation
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