Initial renal function and type of chemotherapy: impact on treatment efficacy in patients with chronic lymphocytic leukemia
- Authors: Nikitina A.K.1,2, Saraeva N.O.1,2
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Affiliations:
- Irkutsk State Medical University
- 1 Krasnogo Vosstaniya St., Irkutsk, 664003, Russia
- Issue: Vol 10, No 1 (2015)
- Pages: 24-28
- Section: HEMATOLOGIC MALIGNANCIES: DIAGNOSIS, TREATMENT, SUPPORTIVE CARE
- Published: 04.06.2015
- URL: https://oncohematology.abvpress.ru/ongm/article/view/135
- DOI: https://doi.org/10.17650/1818-8346-2015-1-24-28
- ID: 135
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Abstract
The paper presents an assessment of treatment efficacy in chronic lymphocytic leukemia CLL patients according to chemotherapy type and initial renal function. The high efficacy of chemotherapy with fludarabine in CLL patients with or without renal failure at diagnosis was revealed. However, regardless of chemotherapy type initial treatment response was worse in patients with renal failure.
About the authors
A. K. Nikitina
Irkutsk State Medical University; 1 Krasnogo Vosstaniya St., Irkutsk, 664003, RussiaRussian Federation
N. O. Saraeva
Irkutsk State Medical University; 1 Krasnogo Vosstaniya St., Irkutsk, 664003, Russia
Author for correspondence.
Email: saraeva2002@mail.ru
Russian Federation
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