Invasive fungal diseases in recipients of allogeneic hematopoietic stem cells: current state of the problem

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Abstract

Allogeneic hematopoietic stem cell transplantation is a standard treatment option for a variety of hematological disorders. In recent years, there has been observed an increase in transplantation activity worldwide as well as in use of alternative donors. Despite introduction of antifungal prophylaxis, recipients of allogeneic hematopoietic stem cells still have a high risk of invasive fungal disease.
This review represents risk factors, frequency and structure of invasive fungal disease in this category of patients.

About the authors

D. A. Mironova

National Medical Research Center for Hematology, Ministry of Health of Russia

Author for correspondence.
Email: mrnvdaria@gmail.com
ORCID iD: 0000-0001-9230-6960

Daria Aleksandrovna Mironova

4 Novyy Zykovskiy Proezd, Moscow 125167

Russian Federation

L. A. Kuzmina

National Medical Research Center for Hematology, Ministry of Health of Russia

ORCID iD: 0000-0001-6201-6276

4 Novyy Zykovskiy Proezd, Moscow 125167

Russian Federation

G. A. Klyasova

National Medical Research Center for Hematology, Ministry of Health of Russia

ORCID iD: 0000-0001-5973-5763

4 Novyy Zykovskiy Proezd, Moscow 125167

Russian Federation

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